高位中枢对刺激下丘脑乳头体核及其周围区域引起的心律失常的影响

首都医科大学学报 ›› 1984, Vol. 5 ›› Issue (2): 106-111.

高位中枢对刺激下丘脑乳头体核及其周围区域引起的心律失常的影响

张茂先, 林波, 张英才

北京第二医学院生理教研室

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1984-04-15 发布日期:1984-04-15

Effects of Higher Centres on Arrhythmias Induced by Stimulation of Hypothalamic Mamillary Body and its Surrounding Regions in Rabbits

Zhang Maoxian

Received:1900-01-01 Revised:1900-01-01 Online:1984-04-15 Published:1984-04-15

摘要/Abstract

摘要： 以单向方波脉冲(波宽0.5～1ms,频率40～70HZ,电流强度5～100μA)刺激麻醉家兔下丘脑乳头体核及其周围区域,刺激期间和刺激停止后可引起持续时间较短的以期前收缩为主的心律失常和动脉血压明显升高。离断间脑以上中枢,并保持动脉血压在70毫米汞柱以上的动物,刺激仍可引起心律失常及动脉血压的显著增高,但对于刺激引起的心律失常反应的敏感性比离断高位中枢前对刺激的反应显著降低。

Abstract: In anesthetized rabbits arrhyt-hmia (mainly ectopie beats)and stiking elevation of arterial blood pressure could be elicited during and after stimulation of mamillary nucleus of the hypothalamus and its surrounding regions with mouopha-sic square wave trains lasted 5 to 15seconds(pulse duration:0.5 to 1 ms;frequency:40 to 70 Hz;current intensity:0.005 to 0.1mA),A redu-ced response of arrhythmia and elevation of blood pressure could still be induced in rabbits with brain stem transected just above the level of dieneephalon and arte-rial blood pressure maintained at a level above 70 mmHg.

张茂先;林波;张英才. 高位中枢对刺激下丘脑乳头体核及其周围区域引起的心律失常的影响[J]. 首都医科大学学报, 1984, 5(2): 106-111.

Zhang Maoxian. Effects of Higher Centres on Arrhythmias Induced by Stimulation of Hypothalamic Mamillary Body and its Surrounding Regions in Rabbits[J]. Journal of Capital Medical University, 1984, 5(2): 106-111.