首都医科大学学报 ›› 1985, Vol. 6 ›› Issue (4): 276-278,269.

• 论著 • 上一篇    下一篇

北京地区汉族人白细胞抗原系统(HLA)的研究 Ⅲ.北京地区汉族人47支白细胞抗原的遗传分析

李哲先1, 高小江1, 郝娃2, 宋长兴1, 孙逸平1, 肖莲珠1, 安家宾1, 胡秀玲1, 费书颖1, 李世良1, 丁素秋3, 贾保祥4, 曹忠正5, 袁庆珍2, 周天栋6   

  1. 1. 北京市结核病肺部肿瘤研究所;2. 北京第二传染病医院;3. 北京市红十字会中心输血站;4. 北京友谊医院;5. 北京第二医学院;6. 北京儿童医院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1985-10-15 发布日期:1985-10-15

Study of the Leucocyte Antigen System among the Han Nationality Population in Beijing Area: Ⅲ. The Genetic Analysis of 47 Leucocyte Antigens of the Han Nationality Population in Beijing Area

Li Zhexian1   

  • Received:1900-01-01 Revised:1900-01-01 Online:1985-10-15 Published:1985-10-15

摘要:

本文对北京地区汉族随机人群中检测出来的39种已知型别抗原(A位点12个,B位点23个,C位点4个)以及8组未知型别抗原指定区,进行了遗传分析。初步建立起一个北京地区汉族人常见型抗原的抗原频率、基因频率、单倍型频率和连锁不平衡参数的遗传模式,并做了Hardy—Weinberg平衡吻合度检验。

Abstract:

We analysed 39 known type antigens that had been tested upon in the random population of the Han Nationality in Beijing area, among them A locus 12, B locus 23, C locus had 4, and 8 unknown type designated region of the antigen and estabilished a tentative model of phenotype frequencies, gene frequencies, hapltype frepuencies and linkage disequilibrium paramater of the common type antigens of the Han Nationality in Beijing area, Also the coincidance rate Hardy-weinberg balance had been carried out.