首都医科大学学报 ›› 1987, Vol. 8 ›› Issue (2): 131-133.

• 论著 • 上一篇    下一篇

国人服用阿斯匹林预防血栓形成的最佳剂量的研究

庞式琪, 孟家眉, 袭书琴, 张津, 温玫, 耿永辉, 宋淑珍   

  1. 首都医学院宣武医院脑血管病研究室
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1987-04-15 发布日期:1987-04-15

Research on Critical Dose for Antithrombotic Effectiveness of Aspirin in Chinese

Pang Shiqi   

  1. Beijing Xuanwu Hospital
  • Received:1900-01-01 Revised:1900-01-01 Online:1987-04-15 Published:1987-04-15

摘要: 以双盲法使139例(男89例,女50例)血小板聚集功能增高者口服安慰剂或分别给予ASA50mg/d,300mg/d、500mg/d,观察服药前后血小板聚集功能变化。结果上述3种ASA剂量对血小板聚集功能均有抑制作用。选用50mg/dASA似最适宜。

关键词: 血小板聚集功能, 预防血栓形成, 最佳剂量

Abstract: We studied 139 cases were taking aspirin due to increased platelet aggregation.89 were males and 50 were females.They were divided into four groups(0,50mg,300mg,500mg,daily)with double-blind method.Platelet aggregation test was performed before and after taking aspirin.Clinical trials demonstrated that therels the benefit of aspirin in males and females.The most optimum dosage of aspirin is 50mg daily.

Key words: platelet aggregation, antithrombotic, critical dose