首都医科大学学报 ›› 1991, Vol. 12 ›› Issue (3): 201-205.

• 论著 • 上一篇    下一篇

肺源性心脏病患者的肝脏形态学研究附30例尸检病例分析

曹大德1, 张敏一2, 翁心植2   

  1. 1. 北京红十字朝阳医院病理科;2. 北京市呼吸疾病医疗研究中心
  • 收稿日期:1990-11-18 修回日期:1900-01-01 出版日期:1991-07-15 发布日期:1991-07-15

Morphological Studies of the Liver in Cor Pulmonale

Cao Dade1, Zhang Minyi2, Weng Xinzhi2   

  1. Department of Pathology, Beijing Red-Cross Chaoyang Hospital
  • Received:1990-11-18 Revised:1900-01-01 Online:1991-07-15 Published:1991-07-15

摘要: 对30例肺心病尸检病例的肝脏形态学变化进行系统的观察,其病理改变表现为肝瘀血、脂肪变性、肝板解离和肝细胞坏死。4例死前有长达7d以上的持续性低氧血症的病例,肝脏发生了小叶中心性大片状肝细胞凝固性坏死,此病变与生前肝功能变化进行了对照分析。作者还发现肺心病病人心衰时间过长可发生肝硬化,其特点是:心衰史多在10a以上;肝硬化的形态特征是反常小叶形成。肺心病人虽也能发生肝硬化,但明显地低于其他类型的心脏病。

关键词: 肺心病, 凝固性坏死, 反常小叶形成

Abstract: The livers of 30 autopsies of cor pulmonale were observed morphorlogically.Hepatic congestion,fatty degeneration,atrophy of hepatic cells,detachment of hepatic plate and the focal necrosis of hepatic cells were the main features among the findings.An acute necrosis of the lobular central hepatic cells resulting from hypoxia appeared in four patients with serious hypoxemia lasting a week.The mechanism of this hepatic cell necrosis was discussed.The author conclude that the patient with cor pulmonale may suffer from cirrhosis,if the heart function is insufficient for a long time.This kind of cirrhosis has the following three characteristics:1.With a long history of heart failure,usually more than 10 years.2.Cirrhosis could follow cot pulmonale,but much less often than other kind of heart diseases. 3.And it is characterized by abnormal lobulation.

Key words: cor pulmonale, coagulation necrosis, abnormal lubolation