首都医科大学学报 ›› 1991, Vol. 12 ›› Issue (1): 49-51.

• 论著 • 上一篇    下一篇

国产盐酸哌吡酮治疗消化性溃疡近期疗效观察

田筱玲, 侯曼芩, 唐秀兰, 田淑萍, 张佩新   

  1. 北京天坛医院内科
  • 收稿日期:1990-02-28 修回日期:1900-01-01 出版日期:1991-01-15 发布日期:1991-01-15

Short Term Effects of Chinese Pirenrepine in the Treatment of Peptic Ulcer

Tian Xiaoling, Hou Manfen, Tang Xiulan   

  1. Department of Radiology, Beijing Stomatological Hospital
  • Received:1990-02-28 Revised:1900-01-01 Online:1991-01-15 Published:1991-01-15

摘要: 将经胃镜确诊为活动性十二指肠球溃疡(60例)和胃溃疡(11例)71例,随机分成两组门诊治疗.分别服用国产盐酸哌吡(艹卓)酮(PRZ,50mg/tid)及甲氰咪胍(200mg/qid),6周后复查胃镜.PRZ组与甲氰咪胍组溃疡愈合率分别为69.5%和50%.PRZ对消化性溃疡近期疗效好,副作用轻微,且可逆.

关键词: 哌吡(艹卓)酮, 消化性溃疡

Abstract: In order to compare the curative effects of Chinese pirenzepine (PRZ) and cimetidine in the treatment of peptic ulcer,71 out-patients with endoscopically documented gastric and duodenal ulcer were treated with either PRZ 50mg three times a day,or cimetidine,200mg four times a day,for six weeks. Endoscopically cured rates were 69.5% and 50% respectively.The statistical significance was P<0.01.Adverse reactions to PRZ were high and reversible.

Key words: pirenrepine, peptic ulcer, random controlled trial