首都医科大学学报 ›› 1993, Vol. 14 ›› Issue (4): 255-257.

• 论著 • 上一篇    下一篇

脉通灵Ⅰ、Ⅱ号对NE、KCl引起的兔主动脉条收缩及AA、ADP诱导的血小板聚集的影响

杨秋生, 赵淑芬, 金有豫   

  1. 首都医学院药理学教研室
  • 收稿日期:1992-07-10 修回日期:1900-01-01 出版日期:1993-10-15 发布日期:1993-10-15

The Effects of Mai Tong Ling Ⅰ,Ⅱ on the Contraction of Rabbit Aortic Strips Initiated by NE and KCl and on Platelet Aggregation Induced by AA and ADP

Yang Qiusheng, Zhao Shufen, Jin Youyu   

  1. Department of Pharmacology, Capital Institute of Medicine
  • Received:1992-07-10 Revised:1900-01-01 Online:1993-10-15 Published:1993-10-15

摘要: 研究了脉通灵Ⅰ、Ⅱ号对家兔主动脉条收缩及血小板聚集的影响.结果表明:脉通灵Ⅰ、Ⅱ号(50~150g/L)对NE、KCl引起的主动脉条收缩有明显的抑制作用;当浓度为66.7~4.2g/LPRP时,对AA、ADP诱导的血小板聚集也有较强的抑制作用。

关键词: 脉管炎, 主动脉条收缩, 血小板聚集

Abstract: We investigated the effects of Mai Tong Ling Ⅰ,Ⅱ on the contraction of rabbit aortic strips and the aggregation of platelets.The results showed that Mai Tong Ling Ⅰ,Ⅱ at the concentration of 50~150g/L reduced the aortic contraction initiated by NE and KCI.In the experiments with rabbit platelet,the aggregation induced by AA(0.21~0.39 mmol)and ADP(8~18 mmol)was also inhibited by Mai Tong Ling Ⅰ,Ⅱ(66.7~4.2g/L PRP),re-spectively.

Key words: vasculitis, platelet aggregation, aortic contraction

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