首都医科大学学报 ›› 1992, Vol. 13 ›› Issue (4): 273-276.

• 论著 • 上一篇    下一篇

美降脂对30例高脂血症病人的疗效观察

冯伟捷1, 刘玄重1, 刘金1, 张剑峰1, 彭名炜2, 王孝蓉2, 张月英2, 王淑敏3, 吴烯云3   

  1. 1. 首都医学院附属北京天坛医院内科;2. 首都医学院附属北京天坛医院药剂科;3. 首都医学院附属北京天坛医院检验科
  • 收稿日期:1991-10-31 修回日期:1900-01-01 出版日期:1992-10-15 发布日期:1992-10-15

Observation of the Effects of Lovastatin on Hyperliperdemia

Feng Weijie1, Liu Xuanzhong1, Liu Jin1, Zhang Jianfeng1, Peng Mingwei2, Wang Xiaorong2, Zhang Yueying2, Wang Shunmin3, Wu Xiyun3   

  1. 1. Department of Internal Medicine, Beijing Tiantan Hospital, Capital Institute of Medicine;2. Department of Pharmacy, Beijing Tiantan Hospital, Capital Institute of Medicine;3. Clinical Laboratory, Beijing Tiantan Hospital, Capital Institute of Medicine
  • Received:1991-10-31 Revised:1900-01-01 Online:1992-10-15 Published:1992-10-15

摘要: 30例血浆胆固醇(TC)>6.5 mmol/L的病人服用美降脂12周后,血浆TC、载脂蛋白B(ApoB)明显降低,血浆HDL-C浓度提高。该药对高甘油三脂(TG)血症也有一定疗效。对载脂蛋白A1(ApoA1)影响不明显。

关键词: 美降脂, 血脂异常症, 治疗

Abstract: Thirty patients with their serum total cholesterol level (TC)>250 mg/dl were pre-scribed lovastatin for 12 weeks and observed.The results showed that lovastatin was signifi-cantly efficacious in decraesing TC,apoprotein B and TC/HDL-C concentration as well as in raising the concentration of high density lipidprotein cholesterol (HDL-C) in serum.Lovas-tatin was efficacious to some exteut in affecting triglyceride (TG) and not effecacious in af-fecting apoprotein A1.

Key words: lovastatin, dyslipidemia, treatment

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