首都医科大学学报 ›› 1993, Vol. 14 ›› Issue (2): 112-115.

• 论著 • 上一篇    下一篇

大鼠坐骨神经复合动作电位参数分析

曲瑞瑶1, 吕国蔚2, 何国瑞2, 何京延2   

  1. 1. 首都医学院生理学教研室;2. 首都医学院神经生物学研究室
  • 收稿日期:1992-10-07 修回日期:1900-01-01 出版日期:1993-04-15 发布日期:1993-04-15

Analysis of Compound Action Potential Parameters of the Sciatic Nerve in Rats

Qu Ruiyao1, Lü Guowei2, He Guorui2, He Jingyan2   

  1. 1. Department of Neurobiology, Capital Institute of Medicine;2. Department of Physiology, Capital Institute of Medicine
  • Received:1992-10-07 Revised:1900-01-01 Online:1993-04-15 Published:1993-04-15

摘要: 用细胞外记录技术,记录了电刺激大鼠腓肠神经引起的坐骨神经复合动作电位,测量与分析了有关刺激参数与动作电位参数.结果表明,电刺激可依次引起 Aα、Aβ、Aγ、Aδ和 C 波。A 波最明显,C波最小并呈双相;A 波的阈强度、最适强度、幅度和传导速度等参数与 C 波的相应参数之间具有极显著的差异;A 波各亚成分的传导速度之间亦具有极显著的差异;动作电位的幅度与传导速度、刺激参数的阈强度与最适强度之间具有正变关系;阈强度、最适强度与传导速度或幅度之间呈指数负相关.结果提示,复合动作电位各成分的传导速度是说明和区分纤维类别的基本依据,幅度、阈强度和最适强度等参数在说明和区分纤维类别上也具有一定的理论与实用价值.

关键词: 复合动作电位, 阈强度, 最适强度, 幅度, 传导速度

Abstract: The compound action potential produced by stimulation of the superficial peroneal nerve were extracellulary recorded from the scintic nerve of rats and their parameters were mea- sured and analysed in the present study.Waves Aα,Aβ,Aγ,Aδ and C were shown in succes- sion upon electrical stimulation.Wave A appeared most distinctly and wave C was smallest in size,showing diphasic in shape.The threshold,optimal strength,amplitude and conduction velocity of wave A were significantly different than the corresponding parameters in wave C.Utmost difference was also shown between subcomponents of wave A.The amplitude of action potential was found to be proportional to the potential's conduction velocity and the threshold and optimal strength of stimuli.Negatively going exponantial correlation was seen between the threshold as well as optimal intensity and the conduction velocity or amplitude. These results indicate that the conduction velocity of various components of compound action potentials is the fundamental basis in describing and identifying different kinds of nerve fibers and that parameters of amplitude,threshold and optimal strength also play their role in explanation and practical application of fiber classification.

Key words: compound action potential, threshold, optimal intensity, amplitude, conduction velocity

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