双降汤与芬氟拉明对大鼠减体重和降脂等作用的比较研究

首都医科大学学报 ›› 1996, Vol. 17 ›› Issue (4): 259-262.

双降汤与芬氟拉明对大鼠减体重和降脂等作用的比较研究

刘素梅¹, 谢燕¹, 武学斌³, 张茂先¹, 李效义¹, 王新荣¹, 魏开元²

1. 首都医科大学生理学教研室;2. 北京师范大学生物系;3. 首都医科大学动物部

收稿日期:1995-12-08 修回日期:1900-01-01 出版日期:1996-10-15 发布日期:1996-10-15

Comparative Study on Body Weight and Fat-reducing Effects of Double-reducing Decoction (Shuang Jiang Tang )and Fenfluramine in Rat

Liu Sumei¹, Xie Yan¹, Wu Xuebin³, Zhang Maoxian¹, Li Xiaoyi¹, Wang Xinrong¹, Wei Kaiyuan²

1. Department of Physiology, Capital University of Medical Sciences;2. Department of Biology, Beijing Normal University

Received:1995-12-08 Revised:1900-01-01 Online:1996-10-15 Published:1996-10-15

摘要/Abstract

摘要： 观察了纯中药复方双降汤和西药芬氟拉明降低大鼠的体重和血脂等作用。结果表明：双降汤可明显降低大鼠体重,对大鼠肥体重(FBW)、附睾脂肪垫重都有不同程度的降低,并能降低血清TC、TG及β-脂蛋白含量,其作用显着优于芬氟拉明,并且副作用小,长期服用安全有效。

关键词: 双降汤, 芬氟拉明, 减体重, 降脂

Abstract: The body weight and fat-reducing effects of double-reducing decoction and fenfluramine was investigated.The results indicated that double-reducing decoction is good for body weight and fat reducing in rat.It can lower body weight after two days of treatment.This effect continued for 90 days until the experiment was over.It can also lower the levels of serum cholesterol, triglycericles and β-lipoprotein.Its effects are better than that of fenfluramine.Double-reducing decoction is high effective, nontoxic and is better than fenfluramine.

Key words: double-reducing decoction, fenfluramine, body weight-reducing effect, fatreducing effect

中图分类号:

R151.1

刘素梅;谢燕;武学斌;张茂先;李效义;王新荣;魏开元. 双降汤与芬氟拉明对大鼠减体重和降脂等作用的比较研究[J]. 首都医科大学学报, 1996, 17(4): 259-262.

Liu Sumei;Xie Yan;Wu Xuebin;Zhang Maoxian;Li Xiaoyi;Wang Xinrong;Wei Kaiyuan. Comparative Study on Body Weight and Fat-reducing Effects of Double-reducing Decoction (Shuang Jiang Tang )and Fenfluramine in Rat[J]. Journal of Capital Medical University, 1996, 17(4): 259-262.