DSP的毒理学安全性研究

首都医科大学学报 ›› 1996, Vol. 17 ›› Issue (3): 205-207.

DSP的毒理学安全性研究

肖忠新, 孔祥环, 尹学钧, 王虹, 唐玉萍

首都医科大学环境卫生教研室

收稿日期:1900-01-01 修回日期:1995-07-19 出版日期:1996-07-15 发布日期:1996-07-15

A Toxicological Study of DSP for Safety Evaluation

Xiao Zhongxin, Kong Xianghuan, Yin Xuejun, Wang Hong, Tang Yuping

Department of Environmental Health, Capital University of Medical Sciences

Received:1900-01-01 Revised:1995-07-19 Online:1996-07-15 Published:1996-07-15

摘要/Abstract

摘要： 对DSP进行了急性毒性及诱变性研究。结果表明：大、小鼠经口LD₅₀均大于600mg/kg体重,小鼠骨髓微核试验、Ames试验及小鼠精子畸形试验均为阴性,未发现有诱变性。

关键词: DSP, 急性毒性, 诱变试验

Abstract: The acute toxicity and mutagenic assays of DSP were carried out.The results showed that the LD50 by the oral route in mice and rats were both more than 600 mg/kg.Micronucleus test of mice bone marrow.Ames test and sperm abnormalities test in mice were all negative and mutagenicity of DSP was not discovered.

Key words: DSP, acute toxicity, mutagenic assays

中图分类号:

R994.1

肖忠新;孔祥环;尹学钧;王虹;唐玉萍. DSP的毒理学安全性研究[J]. 首都医科大学学报, 1996, 17(3): 205-207.

Xiao Zhongxin;Kong Xianghuan;Yin Xuejun;Wang Hong;Tang Yuping. A Toxicological Study of DSP for Safety Evaluation[J]. Journal of Capital Medical University, 1996, 17(3): 205-207.

[1]	高丽芳, 曹丽歌, 田蜜, 胡子净, 郜文. 元宝枫叶提取物的安全性毒理学研究[J]. 首都医科大学学报, 2014, 35(5): 646-652.
[2]	刘东山;张桂芝;金银龙. 挥发性有机物对永生化支气管上皮细胞的急性毒性[J]. 首都医科大学学报, 2005, 26(6): 662-666.