首都医科大学学报 ›› 1997, Vol. 18 ›› Issue (4): 353-355.

• 论著 • 上一篇    下一篇

颅内深部病变94例X-刀分次治疗的随访观察

赵奇煌1, 王琦2, 陈炳桓3   

  1. 1. 北京市第四医院神经外科;2. 北京市第四医院X-刀中心;3. 首都医科大学附属北京天坛医院神经外科
  • 收稿日期:1997-04-16 修回日期:1900-01-01 出版日期:1997-10-15 发布日期:2013-10-28

Long Term Following up of 94 Cases Deep Located Intracranial Lesions after High Dose Stereotactic Fractionated Radiotherapy by X-knife

Zhao Qihuang1, Wang Qi2, Chen Binghuan3   

  1. 1. Department of Neurosurgery, Beijing Fourth Hospital;2. Department o f Neurosurgery Beijing Fourth Hospital;3. Department of Neurosurgery, Beijing Tiantan Hospital, Affiliate of Capital University of Madical Seiences
  • Received:1997-04-16 Revised:1900-01-01 Online:1997-10-15 Published:2013-10-28

摘要: 采用X-刀分次治疗方法对94例颅内深部病变进行了治疗前后的自身对照观察,经治疗后4~38个月(平均24.1个月)随访,疗效满意,病变缩小率50.55%,病变控制率38.46%,症状改善率89.01%。本组约13%的患者出现恶心、呕吐、嗜睡、颅神经麻痹、耳鸣、精神症状等并发症,初步探讨了这些并发症产生的原因及其预防和治疗。

关键词: 加速分割照射, 立体定向, 直线加速器, 颅内病变

Abstract: 94 cases with deep located intracranial lesions were treated with high dose stereotactic fractionated rediotherapy by X-knife. Following up was 4~38 months,mean 24.1 months. Therapeatic evaluation was excellent with the autocontrol of pre post irradation. The shrink ratio of the lesions was 50.55%,the coutrol ratio 38.46%,and the clinical sign improvement ratio 89.01%. The complications,such as nausea,vomiting,lethargy paralysis of cranial nerve,tinnitus and mental symptom were found in 13% cases. This is a first report either in our nation or even in the world on such long term following up study of such a big group patients with deep located intracranial lesions after high dose fractionated stereotactic radiotherapy by X-knife and the author tried to analysed the causes and proventions of the complications.

Key words: fractionated high dose, stereotactic, linear accelerator, intracranial lesions

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