首都医科大学学报 ›› 2000, Vol. 21 ›› Issue (2): 149-151.

• 论著 • 上一篇    下一篇

复发脑膜瘤的临床与超微形态学观察

杨俊1, 孙异临2, 王贵怀1, 张懋植1   

  1. 1. 首都医科大学附属北京天坛医院神经外科;2. 北京市神经外科研究所电镜室
  • 收稿日期:1999-09-01 修回日期:1900-01-01 出版日期:2000-04-15 发布日期:2000-04-15

A Study on Ultrastructure and Clinic Management of Recurrent Meningiomas

Yang Jun1, Sun Yilin2, Wang Guihuai1, Zhang Maozhi1   

  1. Department of Neurosurgery, Beijing Tiantan Hospital, Affiliate of Capital University of Medical Sciences
  • Received:1999-09-01 Revised:1900-01-01 Online:2000-04-15 Published:2000-04-15

摘要: 为探讨脑膜瘤术后复发的原因,对17例复发脑膜瘤术后标本进行了光镜和电镜检查。电镜检查结果显示,17例复发脑膜瘤中有9例瘤内部分细胞生长活跃,而光镜检查结果则显示17例复发脑膜瘤仍为一般脑膜瘤结构表现。提示:对复发脑膜瘤再次手术除力争全切外,还应对肿瘤的组织形态学做超微结构观察。对瘤细胞有生长活跃倾向的病例,建议术后辅以放射治疗,以控制或延缓肿瘤再次复发,延长病人生存期。

关键词: 脑膜瘤, 手术治疗, 超微病理学

Abstract: To demonstrate the causes of recurrence of meningiomas, reviewed their experiences of management in 17 patients with recurrent meningiomas. In every postoperative specimens, the light microscope (LM) and eletronic microscopy (EM) examinations were performed respectively. In 9 cases of 17 patients, the EM analysis revealed the trends to partial malignancy, while in all cases LM examinations exhibited typical nature of benign meningiomas. Conclusions for treatment of reccurent meningiomas, total resection should be emphasized and postopreative ultrastructure examinations of the specimens also be ercommended. It maybe effective for patients who have pathologogical malignancy trends to give adjuvent radiotherapy to improve the prognosis.

Key words: meningiomas, operative treatment, ultrastructure pathology

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