首都医科大学学报 ›› 2001, Vol. 22 ›› Issue (1): 52-54.

• 论著 • 上一篇    下一篇

重症乙肝患者肝、胰组织内HBsAg、HBcAg的检测及其与糖代谢异常关系的探讨

李雪梅1, 郎振为1, 崔世昌1, 朱仁平1, 廖惠钰1, 秦天云2   

  1. 1. 北京佑安医院肝病二科;2. 呼和浩特市第二医院
  • 收稿日期:2000-03-02 修回日期:1900-01-01 出版日期:2001-01-15 发布日期:2001-01-15

Relationship between Abnormal Glucose Metabolism and Existence of HBsAg and HBcAg in Liver and Pacreatic Tissues from Patients with HBV Infection

Li Xuemei1, Lang Zhenwei1, Cui Shichang1, Zhu Renping1, Liao Huiyu1, Qin Tianyun2   

  1. 1. Department of Hepatitis No.2, Beijing Youan Hospital;2. Huhehaote Second Hospital
  • Received:2000-03-02 Revised:1900-01-01 Online:2001-01-15 Published:2001-01-15

摘要: 为探讨乙型肝炎病毒(HBV)感染患者肝、胰组织中HBV检出情况及其与糖代谢异常之间的关系,采用免疫组化法对22例重症HBV感染伴糖代谢异常患者的尸解肝、胰组织中HBsAg、HBcAg进行检测.同时用22例空腹血糖正常的HBV感染者的尸解肝、胰组织作为对照.结果:肝病伴糖代谢异常组与对照组胰腺组织内HBV检出例数有显着性差异(P<0.05).提示:乙型肝炎患者胰腺组织HBV感染可能是发生肝病伴糖代谢异常的原因之一.

关键词: 乙型肝炎病毒(HBV), 肝脏, 胰腺, 糖代谢异常, 免疫组化

Abstract: To study the relationship between the abnormality of glucose metabolism and the existence HBsAg and HBcAg in liver and pacreatic tissues from autopsy patients with HBV infection, samples taken from 22 cases were detected by immunohistochemistry. In the meantime, 22 cases with normal blood sugar were selected as control group. Result: There was remarkable HBV difference in pacreatic tissues between the hepatic group with the abnormal glucose metabolism and the control group(P<0.05). The data shows that HBV infection in pancreas tissues might be one of the causes of the hepatic with the abnormal glucose metabolism.

Key words: hepatitis B virus(HBV), liver, pancreas, abnormal glucose metabolism, immunohistochemical method

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