首都医科大学学报 ›› 2003, Vol. 24 ›› Issue (3): 293-295.

• 论著·临床研究 • 上一篇    下一篇

辣椒碱与双氯芬酸二乙胺治疗关节痛疗效的比较研究

李小霞, 黄旭, 张红宇   

  1. 首都医科大学宣武医院风湿科
  • 收稿日期:2003-02-21 修回日期:1900-01-01 出版日期:2003-07-15 发布日期:2003-07-15

Comparison of Drug Capsaicin with Drug Diclofenac Diethyl Ammonium in the Treatment Arthralgia

Li Xiaoxia, Huang Xu, Zhang Hongyu   

  1. Department of Rheumatology, Xuanwu Hospital, Affiliate of Capital University of Medical Sciences
  • Received:2003-02-21 Revised:1900-01-01 Online:2003-07-15 Published:2003-07-15

摘要: 为了解辣椒碱软膏治疗关节痛的疗效及安全性,将46例有明确关节痛的患者,随机分为治疗组、对照组,各组均为23例,用双盲法进行对比验证。治疗组应用0.025%辣椒碱软膏,对照组应用1%双氯芬酸二乙胺乳胶剂,2组用法均为外涂治疗1周。结果:2组患者在关节疼痛、压痛和活动痛方面均有明显的疗效,总有效率分别为82.61%和86.37%,2组的耐受性均比较好。提示:辣椒碱软膏治疗关节痛有效、安全。

关键词: 关节痛, 辣椒碱, 双氯芬酸二乙胺

Abstract: To evaluate the efficacy and safety of topical capsaicin cream in treatment of arthralgia in comparison with diethyl ammonium emulsion, 46 patients with arthralgia were randomly divided to receive 0.025% capsaicin cream (n=23) or 1% diclofenac diethyl ammonium emulsion (n=23) for 1 week. The symptoms of arthralgia in both groups were significantly reduced and the degree of arthralgia on movement in both groups were diminished. In conclusion, capsaicin cream is effective, safe in the treatment of arthralgia.

Key words: arthralgia, capsaicin, diclofenac diethyl ammonium

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