宫颈癌保留神经手术后排尿功能评价

doi:10.3969/j.issn.1006-7795.2024.05.016

首都医科大学学报 ›› 2024, Vol. 45 ›› Issue (5): 853-857.doi: 10.3969/j.issn.1006-7795.2024.05.016

• 泌尿系疾病的综合治疗 • 上一篇下一篇

宫颈癌保留神经手术后排尿功能评价

靳琼¹,董德鑫², 赵越³,耿宇宁^1*

1. 首都医科大学附属北京妇产医院/北京妇幼保健院妇瘤科，北京 100026；2. 中国医学科学院北京协和医院泌尿外科，北京 100005；3. 首都医科大学附属北京妇产医院/北京妇幼保健院内分泌科，北京 100026

收稿日期:2024-05-27 出版日期:2024-10-21 发布日期:2024-10-18
通讯作者: 耿宇宁 E-mail:gengyuning0118@mail.ccmu.edu.cn
基金资助:
中国妇女盆底功能障碍防治专项（201801002），北京市医院管理中心“登峰”计划专项经费资助项目(DFL20221201)，首都医科大学基础临床科研合作课题(17JL27)，首都医科大学附属北京妇产医院中青年学科骨干培养专项(FCYY201921)。

Postsurgical urodynamic study of nerve-sparing radical hysterectomy in the treatment of cervical cancer

Jin Qiong¹, Dong Dexin², Zhao Yue³, Geng Yuning^1*

1. Department of Gynecological Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University/Beijing Maternal and Child Health Care Hospital, Beijing 100026, China; 2. Department of Urology Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100005, China; 3. Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University/Beijing Maternal and Child Health Care Hospital, Beijing 100026, China

Received:2024-05-27 Online:2024-10-21 Published:2024-10-18
Supported by:
This study was supported by the Special Research Funding for the Prevention and Treatment of Pelvic Floor Dysfunction in Chinese Women (201801002)， Beijing Hospitals Authority's Ascent Plan (DFL20221201), Capital Medical University (17JL27), Beijing Obstetrics and Gynecology Hospital, Capital Medical University（FCYY201921）.

摘要/Abstract

摘要： 目的探讨宫颈癌保留神经的广泛性子宫切除术（nerve sparing radical hysterectomy，NSRH）治疗宫颈癌的效果及对排尿功能的影响。方法纳入2019年5月至2022年5月于首都医科大学附属北京妇产医院就诊并诊断为宫颈癌的患者55例，国际妇产科联盟分期分布在ⅠB至ⅡA2。其中28例患者接受了NSRH（NSRH组），27例患者接受了广泛性全子宫切除术（radical hysterectomy，RH）（RH组）。比较2组患者手术相关指标及术后排尿功能。结果 NSRH组平均年龄为(51.0±7.9)岁，RH组平均年龄为(46.3±8.5)岁，年龄分布差异有统计学意义（P<0.05）。2组出血量差异无统计学意义（P>0.05）。2组患者手术切缘均为阴性。术后病理提示阴道长度、淋巴结转移、间质浸润深度、淋巴脉管浸润比较差异均无统计学意义（P>0.05）。在术后膀胱功能方面，NSRH组残余尿较RH组多（P<0.05），但NSRH组拔尿管的时间较RH组明显缩短（P<0.05）。结论 NSRH能够在确保手术范围的同时，减轻对术后排尿功能的影响，缩短术后恢复时间。

关键词: 宫颈肿瘤, 保留神经的广泛子宫切除术, 排尿功能

Abstract: Objective To compare bladder function between nerve-sparing radical hysterectomy (NSRH) and radical hysterectomy (RH) for patients with uterine cervical cancer. Methods This prospective study enrolled 55 patients with cervical cancer between May 2019 and May 2022 at the Department of Gynecological Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University: with 28 in the NSRH group and 27 in the AH group. Information of patients with stages ⅠB to ⅡA cervical cancer were collected according to the inclusion criteria. Demographic, surgical, and oncological data were collected. Results The average age in the NSRH group was(51.0±7.9) years, and (46.3±8.5) years in the RH group, with significant statistical difference (P<0.05). There was no significant difference between the two groups in operation duration, blood loss, vaginal length, lymph node metastasis(P>0.05), depth of stromal invasion, or lymphovascular invasion in the postoperative pathology(P>0.05). Residual urine in NSRH group was more than that in RH group(P<0.05). However, the time to postoperative catheter removal was significantly shorter in NSRH group(P<0.05).Conclusions NSRH can effectively promote the postoperative bladder function of patients with cervical cancer, thereby shortening the recovery time after surgery.

Key words: uterine cervical neoplasms, nerve-sparing radical hysterectomy, postsurgical urodynamic

中图分类号:

靳琼, 董德鑫, 赵越, 耿宇宁. 宫颈癌保留神经手术后排尿功能评价[J]. 首都医科大学学报, 2024, 45(5): 853-857.

Jin Qiong, Dong Dexin, Zhao Yue, Geng Yuning. Postsurgical urodynamic study of nerve-sparing radical hysterectomy in the treatment of cervical cancer[J]. Journal of Capital Medical University, 2024, 45(5): 853-857.

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宫颈癌保留神经手术后排尿功能评价

Postsurgical urodynamic study of nerve-sparing radical hysterectomy in the treatment of cervical cancer

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