首都医科大学学报 ›› 2015, Vol. 36 ›› Issue (1): 40-44.doi: 10.3969/j.issn.1006-7795.2015.01.008

• 血管外科专题 • 上一篇    下一篇

经皮腔内血管成形术治疗下肢缺血膝下病变

谭正力1, 缪鹏1, 田然1, 宋希涛2, 李树国1, 刘昌伟2, 郁正亚1   

  1. 1. 首都医科大学附属北京同仁医院血管外科 首都医科大学血管外科学系, 北京 100730;
    2. 北京协和医院血管外科中心, 北京 100730
  • 收稿日期:2014-11-15 出版日期:2015-02-21 发布日期:2015-01-31
  • 通讯作者: 郁正亚 E-mail:zhengyayu_tr@126.com
  • 基金资助:
    首都医学科学发展基金(2009-2001).

Percutaneous transluminal angioplasty for treatment of below-the-knee arterial lesion

Tan Zengli1, Liao Peng1, Tian Ran1, Song Xitao2, Li Shuguo1, Liu Changwei2, Yu Zhengya1   

  1. 1. Department of Vascular Surgery, Beijing Tongren Hospital, Capital Medical University, Department of Vascular Surgery, Capital Medical University, Beijing 100730, China;
    2. Department of Vascular Surgery, Peking Union Medical College Hospital, Beijing 100730, China
  • Received:2014-11-15 Online:2015-02-21 Published:2015-01-31
  • Supported by:
    This study was supported by Capital Medical Development Foundation(2009-2001).

摘要: 目的 探讨经皮腔内血管成形术治疗下肢缺血膝下病变在Rutherford Ⅱ~Ⅵ不同分级的临床治疗效果.方法 回顾分析首都医科大学附属北京同仁医院及北京协和医院血管外科2011年至2013年收治的189例下肢缺血膝下病变(blow the knee,BTK)行腔内血管成形术患者(207条肢体).术前按Rutherford分级分组,术后随访并计算其临床症状缓解率、一期通畅率、生存率和保肢率.结果 共入选患者189例, 207条患肢.患者平均年龄(71.33±6.90)岁.其中,糖尿病148例、吸烟60例、高血压病124例、高脂血症90例、冠状动脉粥样硬化性心脏病(以下简称冠心病)58例、肾功能不全21例、脑血管病30例.患肢Rutherford分级Ⅱ~Ⅲ级45条、Ⅳ级71条、Ⅴ~Ⅵ级91条.平均随访时间(21.8±5.2)个月,总体病死率7.41%.Rutherford Ⅱ~Ⅲ级术后第1年、第2年保肢率分别为97.56%和93.81%,Ⅳ级术后第1年、第2年的保肢率分别为92.55%和87.86%,Ⅴ~Ⅵ级术后第1年、第2年的保肢率分别86.50%和77.58%.术后1年一期通畅率分别为86.85%、67.12%、50.54%,2年的一期通畅率分别为65.14%、54.67%、37.68%.结论 经皮腔内血管成形术治疗严重下肢缺血合并膝下病变安全、有效,虽然中期随访通畅率较低,但保肢率较高,可以作为首选治疗方法.

关键词: 膝下动脉, 血管成形术, 外周血管疾病, Rutherford

Abstract: Objective To report our experience in treating patients with below-the-knee (BTK) arterial lesions, Rutherford class Ⅱ-Ⅵ, with percutaneous transluminal angioplasty (PTA).Methods A retrospective analysis of BTK arterial angioplasty procedures was performed. Patients were classified according to different Rutherford stages. SVS runoff scores were determined after the completion of the intervention and tansluminal angioplasty (PTA) of infrapopliteal artery for the treatment of patients with lower extremity ischemia at Rutherford Ⅱ-Ⅵ stages. Data of 207 cases who underwent peripheral angioplasties for BTK arterial diseases in 189 patients seen from 2010 to 2014 were collected, stratified by Rutherford class, in two vascular surgery medical centers. Data included primary patency, limb salvage, and target vessels patency assessed by Kaplan-Meier life-table analysis.Results There were 189 patients (mean age 71.33±6.90 years) who received PTA surgeries, including 148 patients with diabetes, 60 smoking, 90 with hyperlipidemia, 124 with hypertension, 58 with coronary artery disease, 21 with renal insufficiency and 30 with cerebral infarction. Rutherford stage Ⅱ- Ⅲ diseases were seen in 45 limbs, stage IV in 21 limbs, and stage V-VI in 91 limbs. At the mid-term follow-up (21.8±5.2 months), the overall death rate was 7.94%. The limb salvage rates of Rutherford class Ⅱ-Ⅲ patients in 1 and 2 years postoperatively were 97.56% and 93.81%, respectively, in class IV patients 92.55% and 87.86%, respectively, and in class V-Ⅵ patients 86.50% and 77.58%, respectively. Primary patency rates the 1st year postoperatively were 86.85%, 67.12%, 38.78% and 65.14%, 54.67%, 37.68% at the 2nd years. Conclusion Our results showed that the patency rate as an intermediate clinical outcome of infrapopliteal PTA was low. But it had higher limb salvage rate and higher symptoms relief rate. These data suggested that PTA should be considered as initial therapy for treatment of below-the-knee lesion.

Key words: inferior genicular artery, angioplasty, peripheral arterial disease, Rutherford

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