大鼠肝部分切除后甲状腺组织学和免疫组织化学变化

首都医科大学学报 ›› 1986, Vol. 7 ›› Issue (4): 253-257,331.

大鼠肝部分切除后甲状腺组织学和免疫组织化学变化

李玲凤, 孙克继, 刘英琴, 朱琳

北京第二医学院组织胚胎学教研室

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1986-10-15 发布日期:1986-10-15

ABSTRACT OF ORIGINAL ARTICLES Histological and Immunohistochemical Changes of the Rat Thyroid Gland after Partial Hepatectomy

Li Lingfeng

Department of Histology and Embryology

Received:1900-01-01 Revised:1900-01-01 Online:1986-10-15 Published:1986-10-15

摘要/Abstract

摘要：

应用组织学和免疫组织化学方法,观察大鼠肝部分切除后1、2、8、7和14天期间甲状腺滤泡上皮细胞的变化。假手术后滤泡上皮细胞分泌机能有所降低,可能与应激反应有关,肝大部切除后,滤泡上皮细胞明显增高,胞质内胶体小滴的数量和T₃、T₄免疫反应物的量均增加。这些变化以术后2—3天最明显,到术后第14天渐趋正常。提示肝大部切除后,特别是术后2—3天,滤泡上皮细胞分泌活动增进。肝小部切除后,滤泡上皮细胞的变化特点和趋势与肝大部切除的相似,但变化程度较轻。本文结果说明,甲状腺滤泡上皮细胞的变化与肝再生间存在着密切的关系。

Abstract:

The present study was designed to investigate the histological andimmunohistochemical changes of the thyroid follicular epithelial cells,during 1,2,3,7 and 14 days following partial hepatectomy.After thesham operation,the secretion activity of follicular epithelial cellsdeclined and were probably related to stress reaction.After largeportion hepatectomy,the follicular epithelial cells bccame heightenedapparently.Both the amount of colloid droplets and the immunoreactionsubstance of T₃,T₄,increased.2-3 days after operation,these changeswere most prominant;14 days later,such changes recovered graduallyto normal level.The above mentioned changes suggested that thesecretory activity of follicular epithelial cells increascd.After smallprotion hepatectomy,the changes of the follicular epithelial cells wereless marked.By analogy with the liver regenerative process,all thefindings suggested that the morphological and secretory activity changesof the follicular epithelia cells were closely related with liverregeneration.

李玲凤;孙克继;刘英琴;朱琳. 大鼠肝部分切除后甲状腺组织学和免疫组织化学变化[J]. 首都医科大学学报, 1986, 7(4): 253-257,331.

Li Lingfeng. ABSTRACT OF ORIGINAL ARTICLES Histological and Immunohistochemical Changes of the Rat Thyroid Gland after Partial Hepatectomy[J]. Journal of Capital Medical University, 1986, 7(4): 253-257,331.