首都医科大学学报 ›› 1986, Vol. 7 ›› Issue (4): 287-288,336,286.

• 论著 • 上一篇    下一篇

肝癌患者血清铜和锌浓度的变化

袁振铎, 徐婉珍, 朱圭如   

  1. 北京市临床医学研究所生化研究室
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1986-10-15 发布日期:1986-10-15

Changes of Serum Copper and Zinc Conceatration in Patients With Hepatic Cancer

Yuan Zhenduo   

  1. Beijing Clinical Medicine Research Institute
  • Received:1900-01-01 Revised:1900-01-01 Online:1986-10-15 Published:1986-10-15

摘要:

用原子吸收分光光度计测定了66例健康成年人及17例肝癌惠者血清铜和锌浓度。健康人血清铜平均浓度126.40±23.44μg/100ml(X±SD),锌116.12±25.60μg/100ml.17例肝癌患者血清铜明显增高,平均浓度为155.83±37.08μg/100ml(P<0.001),血清锌降低为86.72±31.89μg/100ml(P<0.001)。血清Cu/Zn 比值明显的增加(正常值为1.12±0.32;肝癌时为2.15±0.31,P<0.001)。结果提示血清铜锌浓度及比值测定对诊断肝癌有一定意义。

Abstract:

Serum copper and zinc of 66 healthy adults and 17 patients with hepaticcancer were determined by atomic absorption spectrophotometry.Themean concentration of serum copper in healthy blood donors and volunteerswas 126.40±23.44μg/100ml(X±S.D),and zinc was 116.12±25.60μg/100ml.Theconcentration of serum copper was markedly increased in 17 patientswith hapatic cancer,in which the mean serum copper was 155.83±37.08μg/100ml(P<0.001).Whereas,serum zinc decreased in great degree(86.72±31.89μg/100ml,P<0.001).Serum Cu/Zn ratio increasedconspicuously(1.12±0.30→2.15+0.31,P<0.001).