橡胶防老剂D致突作用研究

首都医科大学学报 ›› 1987, Vol. 8 ›› Issue (3): 190-192.

橡胶防老剂D致突作用研究

邢卫荣, 苏忆兰, 蒋建民

首都医学院卫生学教研室

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1987-07-15 发布日期:1987-07-15

The Mutation of Antioxidant D

Xing Weirong

Department of Public Health

Received:1900-01-01 Revised:1900-01-01 Online:1987-07-15 Published:1987-07-15

摘要/Abstract

摘要： 防老剂D是以N-苯基-β-萘胺为主要成份的一种橡胶工业污染物。亦是一种可疑的致突、致癌物或协同致突、致癌物。本文的研究结果发现防老剂D能显著地增加小鼠骨髓多染红细胞和大鼠胎鼠肝多染红细胞的微核发生率,说明防老剂D是一种致突物,具有胚胎毒性。

关键词: 防老剂 D, 多染红细胞, 微核

Abstract: The antioxidant Dmainly containing N-pbenyl-2-naphthyl-amine was a pollutant of the rubber industry.It was suspected a mutagen, carcinogen or comutagen,cocarinogen.This paper indicated that the antioxidant D significantly elevated the rate of the micronuclei in the mouse bone-marrow polychromatid erythrocytes and in the liver polychromatid erythrocytes cells of the foetus rat.It suggested that the antioxidant D is a mutagen,carcinogen and has the genetic toxciity of tne foetus.

Key words: antioxidant D, polychromatid erythrocytes, micronucleus

邢卫荣;苏忆兰;蒋建民. 橡胶防老剂D致突作用研究[J]. 首都医科大学学报, 1987, 8(3): 190-192.

Xing Weirong. The Mutation of Antioxidant D[J]. Journal of Capital Medical University, 1987, 8(3): 190-192.

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