辐照北京烤鸭的毒理学安全性评价研究 动物亚慢性毒性试验及染色体畸变分析

首都医科大学学报 ›› 1987, Vol. 8 ›› Issue (4): 268-273.

辐照北京烤鸭的毒理学安全性评价研究动物亚慢性毒性试验及染色体畸变分析

王惠琴¹, 蒋保季¹, 蒋致诚¹, 崔允文², 史月西³, 陈振良¹, 张宏卫¹, 罗政红¹, 苏忆兰¹, 赵淑珍¹

1. 首都医学院卫生学教研室;2. 首都医学院生物学教研室;3. 首都医学院病理解剖学教研室

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1987-10-15 发布日期:1987-10-15

Evaluation of Toxicological Safety of Irradiated Beijing Roast-Duck

Wang Huiqin¹

Department of Public Health

Received:1900-01-01 Revised:1900-01-01 Online:1987-10-15 Published:1987-10-15

摘要/Abstract

摘要： 对饲以含22%的经⁶⁰COγ射线2000戈瑞辐照的北京烤鸭肉粉和4%鸭油饲料的大鼠和小鼠进行亚慢性毒性实验和染色体畸变分析。结果表明实验组和对照组在生长发育、食物利用系数、血液常规和特定生化指标、脏体比和脏器病理检查等方面均无统计学上的显著性差异。两组动物的骨髓细胞和睾丸细胞的染色体畸变率也无显著差异。研究表明该辐照北京烤鸭对实验动物无毒理学有害影响。

关键词: 安全性评价, 辐照, 烤鸭

Abstract: The sub-chronic toxic test and chromosome aberration ana lysis of rats and mice were examined.The animals were fed with the diet that contain 22% muscle and 4%fat of the Beijing roast-duck which were irradiated by 60Co-ray with 20KGY.The results showed that there were no statistical significant difference between the experimental animals and controls in the parameters of the growth ratio,coefficiency of died utilization,routine and specific test of blood, viscera wt/body ratio and pathological inspection.There were also no statistical significant difference between the two groups in the chromosome aberration ratio of the cells from bone marrow of rats and the cells of testis of mice.This study shows that such a irradiated Beijing roast-duck has no toxicological harmful intluence to the experimental animals.

Key words: sakety evaluation, irradiation, roast-duck

王惠琴;蒋保季;蒋致诚;崔允文;史月西;陈振良;张宏卫;罗政红;苏忆兰;赵淑珍. 辐照北京烤鸭的毒理学安全性评价研究动物亚慢性毒性试验及染色体畸变分析[J]. 首都医科大学学报, 1987, 8(4): 268-273.

Wang Huiqin. Evaluation of Toxicological Safety of Irradiated Beijing Roast-Duck[J]. Journal of Capital Medical University, 1987, 8(4): 268-273.

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