丹参注射液对大鼠部份肝切除后肝脏再生的影响

首都医科大学学报 ›› 1987, Vol. 8 ›› Issue (4): 286-290.

丹参注射液对大鼠部份肝切除后肝脏再生的影响

李莜桦, 陈裕信

北京红十字朝阳医院外科

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1987-10-15 发布日期:1987-10-15

Effect of Salvia Miltiorrhiza Injection to Liver Regeneration of Partially Hepatectomized Rats

Li Xioahua, Chen Yuxin

Department of Surgery, Beiging Red-Cross Chaoyang Hospital

Received:1900-01-01 Revised:1900-01-01 Online:1987-10-15 Published:1987-10-15

摘要/Abstract

摘要： 实验观察丹参注射液对大鼠部份肝切除后肝脏DNA合成率、DNA含量,肝细胞标记核数、肝细胞核分裂相以及再生肝重变化的影响,探讨了丹参对肝再生的促进作用.实验结果表明丹参注射液能够促进肝脏再生时的DNA合成和细胞分裂增殖过程,具有一定的促进肝再生作用。丹参的这种作用可能是通过改善肝脏局部血液循环,加强肝再生内在因素的作用而实现的。丹参促进肝再生作用具有一定的临床意义。它可以作为肝切除后恢复期的辅助药物,同时对其它肝脏疾病也可能有一定的治疗作用.

关键词: 丹参, 脱氧核糖校酸合成, 肝再生, 肝切除

Abstract: The aim of our experiment is to observe the positive effect of Salvia Miltiorrhiza to liver regeneration of partially hepatectomized rats through the rate of DNA synthesis,DNA content,labelled nuclei, mitosis and regenerating liver weight. The results indicated that Salvia Mihiorrhiza has the effect to promote DNA synthesis and cell proliferation during liver regeneration.We suppose that the positive effect is achieved through improving local blood circulation and inereaseing the effect of hepatotrophic factors.The effect of Salvia Miltiorrhiza to liver regeneration may be clinically important。 It may be used as a drug for the treatment of post-hepatectomy to premote liver regeneration,and it may also be benefit to other liver diseases.

Key words: Salvia Miltiorrhiza, DNA Synthesis, liver regeneration, hepatectomy

李莜桦;陈裕信. 丹参注射液对大鼠部份肝切除后肝脏再生的影响[J]. 首都医科大学学报, 1987, 8(4): 286-290.

Li Xioahua;Chen Yuxin. Effect of Salvia Miltiorrhiza Injection to Liver Regeneration of Partially Hepatectomized Rats[J]. Journal of Capital Medical University, 1987, 8(4): 286-290.

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