首都医科大学学报 ›› 1992, Vol. 13 ›› Issue (4): 295-297.

• 论著 • 上一篇    下一篇

正常人心钠素排泄分数的研究

徐宝钢, 汪家瑞, 何士大, 喻玲华, 陈建军, 王宏燕, 温绍君, 曹心民   

  1. 首都医学院宣武医院高血压实验室
  • 收稿日期:1991-12-20 修回日期:1900-01-01 出版日期:1992-10-15 发布日期:1992-10-15

A Study of Fractional Excretion of Atrial Natriuretic Factor in Normal Humans

Xu Baogang, Wang Jiarui, He Shida, Yu Linhua, Chen Jianjun, Wang Hongyan, Wen Shaojun, Cao Xinmin   

  1. Hypertension Research Lab, Xuanwu Hospital, Capital Institute of Medicine
  • Received:1991-12-20 Revised:1900-01-01 Online:1992-10-15 Published:1992-10-15

摘要: 应用高灵敏、高特异放射免疫测定方法,观察了159名正常人的血浆和尿心钠素样物质。结果表明:FEANF与年龄呈正相关(P<0.01),24h内生肌酐清除率随年龄增长而降低(P<0.05),尿心钠素样物质含量与24 h内生肌酐清除率呈负相关(P<0.05)。此外老年组与中青年组FEANF有显著性差异(P<0.001)。

关键词: 心钠素, 心钠素排泄分数, 年龄

Abstract: We measured the plasma and urine concentration of the ANF-like material in 159 nor-mal subjects with a highly sensitive and specific radioimmunoassay.The results showed that there was a positive correlation between FEANF and age (P<0.01 ), and the endogenous cre-atinine clearance rate in 24 hours decreasesed with aging, The urine ANF-like material level increased while the endogenous creatinine clearance rate decreased.In addition, there was a significant difference between elderly group and young group.

Key words: atrial natriuretic factor (ANF), fractional excretion of ANF(FEANF), age

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