抗癫痫药——苯妥英钠诱发小鼠骨髓细胞染色体畸变的研究

首都医科大学学报 ›› 1993, Vol. 14 ›› Issue (1): 23-25.

抗癫痫药——苯妥英钠诱发小鼠骨髓细胞染色体畸变的研究

刘冰¹, 刘荣华², 梁茀祐²

1. 中国中医研究院广安门医院检验科;2. 首都医学院生物学教研室

收稿日期:1991-09-19 修回日期:1900-01-01 出版日期:1993-01-15 发布日期:1993-01-15

Bone Marrow Cell Chromosome Aberration Caused by Phenytion Sodium in Mice

Liu Bing¹, Liu Ronghua², Liang Fuyou²

1. Chinese Medicine Institute Guang'anmen Hospital;2. Biology Department, Capital Institute of Medicine

Received:1991-09-19 Revised:1900-01-01 Online:1993-01-15 Published:1993-01-15

摘要/Abstract

摘要： 对苯妥英钠诱发小鼠骨髓细胞畸变的问题进行了研究。结果表明:苯妥英钠对小鼠骨髓细胞染色体的损伤程度,随荆量的增加而增大,各剂量组与对照组比较均有显著性差异。

关键词: 苯妥英钠, 骨髓细胞, 染色体畸变

Abstract: We studied the effect of phenytion sodium in causing bone marrow cell chromosome aberration in mice.The result showed that the degree of medullary cell chromosome aberra-tion caused by phenytion sodium was increased with the increase of dosage,and there was significant defference between each experimental group and control group.

Key words: phenytion sodium, bonemarrow cell, chromosome aberration

中图分类号:

Q343.245

刘冰;刘荣华;梁茀祐. 抗癫痫药——苯妥英钠诱发小鼠骨髓细胞染色体畸变的研究[J]. 首都医科大学学报, 1993, 14(1): 23-25.

Liu Bing;Liu Ronghua;Liang Fuyou. Bone Marrow Cell Chromosome Aberration Caused by Phenytion Sodium in Mice[J]. Journal of Capital Medical University, 1993, 14(1): 23-25.