大鼠口服红景天致畸作用的研究

首都医科大学学报 ›› 1993, Vol. 14 ›› Issue (2): 90-93.

大鼠口服红景天致畸作用的研究

王惠琴, 孔祥环, 蒋致诚, 陈振良, 刘丽娟, 吴平, 唐玉萍, 沈家芹, 肖忠新

首都医学院预防医学系卫生毒理学教研室

收稿日期:1991-12-23 修回日期:1900-01-01 出版日期:1993-04-15 发布日期:1993-04-15

The Teratogenic Effect of Rhodiola by Oral Administration in Rats

Wang Huiqin, Kong Xianghuan, Jiang Zhicheng, Chen Zhenliang, Liu Lijuan, Wu Ping, Tang Yuping, Shen Jiaqin, Xiao Zhongxin

Department of Hygiene Toxicology, Capital Institute of Medicine

Received:1991-12-23 Revised:1900-01-01 Online:1993-04-15 Published:1993-04-15

摘要/Abstract

摘要： 药用植物红景天提取物具有抗高寒、抗疲劳、抗缺氧等作用,可作为食品新资源开发利用.以红景天0.8、1.6、3.2g/kg 体重分别给怀孕大鼠灌胃,结果除阳性对照组外,各实验组均未出现畸胎.本试验结果为红景天饮料的毒理学安全性评价提供了科学依据.

关键词: 红景天, 食品新资源, 致畸性

Abstract: The extract of rhodiola appear to be effective to help the body to resist and tolerate low temperature,fatigue and oxygen hungry.We propose that it might be possible to be used as a new food resourses and supplement.In our study the extract of rhodiola was given to groups of pregnant rats by stomach-tubing in doses of 0.8g,1.6g and 3.2g/kg of body weight re-spectively.The results showed that there were no teratogenic effects for the experimental groups and the negative control group.However,teratogenic effects for the positive control group was obvious.This results provide the scientific evidence for the evaluation of toxicolo-gy and safety of rhodiola containing beverage.

Key words: rhodiola, new food resources, teratogenicity

中图分类号:

R994.4

王惠琴;孔祥环;蒋致诚;陈振良;刘丽娟;吴平;唐玉萍;沈家芹;肖忠新. 大鼠口服红景天致畸作用的研究[J]. 首都医科大学学报, 1993, 14(2): 90-93.

Wang Huiqin;Kong Xianghuan;Jiang Zhicheng;Chen Zhenliang;Liu Lijuan;Wu Ping;Tang Yuping;Shen Jiaqin;Xiao Zhongxin. The Teratogenic Effect of Rhodiola by Oral Administration in Rats[J]. Journal of Capital Medical University, 1993, 14(2): 90-93.