首都医科大学学报 ›› 1993, Vol. 14 ›› Issue (3): 169-170.

• 论著 • 上一篇    下一篇

大鼠红细胞中超氧化物歧化酶增龄性变化

马忠杰   

  1. 首都医学院营养与食品卫生教研室
  • 收稿日期:1992-03-13 修回日期:1900-01-01 出版日期:1993-07-15 发布日期:1993-07-15

Aging-related Changs of Special Activity of Superoxide Dismutase in Rat Erythrocyte

Ma Zhongjie   

  1. Department of Nutrition and Food Hygiene, Capital Institute of Medicine
  • Received:1992-03-13 Revised:1900-01-01 Online:1993-07-15 Published:1993-07-15

摘要: 应用邻苯三酚自氧化法测定3~4、7~8和12~13月龄 Wistar 大鼠红细胞中的超氧化物歧化酶(SOD)活性,结果分别为:11 409+994、11 098±636、10 310±960 U/g Hb。SOD 活性随增龄递减,12~13与3~4月龄 SOD 比较显著下降。故认为:SOD 可作为衰老诊断的参考指标,支持衰老的自由基学说。

关键词: 衰老, 超氧化物歧化酶, 红细胞

Abstract: SOD was detected with the methods of pyrogallol autoxidation method in the rat of 3~ 4 months,7~8 months and 12~13 months.The results were 11 409±994,11 098±636 and 10 310±960U/g Hb respectively.SOD was decreasing while the age increasing.SOD in the rat of 12~13 months was decreased obviously comparing to the rat of 3~4 months. Therefore,SOD can be served as diagnostic parameters of aging.The theory of free radical in aging was sustained

Key words: aging, superoxide dismutase, erythrocyte

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