首都医科大学学报 ›› 1993, Vol. 14 ›› Issue (4): 261-264.

• 论著 • 上一篇    下一篇

单纯疱疹病毒Ⅱ型感染与宫颈病变的关系

李桂娴1, 刘娜2   

  1. 1. 首都医学院生殖医学研究室;2. 首都医学院解剖学教研室
  • 收稿日期:1992-05-18 修回日期:1900-01-01 出版日期:1993-10-15 发布日期:1993-10-15

Correlation of Cervical Diseases with Herpes Simplex Virus Type 2

Li Guixian1, Liu Na2   

  1. 1. Department of Reproductive Medicine, Capital Institute of Medicine;2. Department of Anatomy, Capital Institute of Medicine
  • Received:1992-05-18 Revised:1900-01-01 Online:1993-10-15 Published:1993-10-15

摘要: 对42例宫颈活检组织用免疫细胞化学的方法检测单纯疱疹病毒Ⅱ型(HSV-2)抗原,探讨其与宫颈病变的关系。结果宫颈鳞癌、宫颈息肉及慢性宫颈炎HSV-2免疫阳性反应的病例数较高,分别占88.9%、77.8%和68.4%,宫颈腺癌和子宫内膜腺癌累及宫颈者均为阴性反应.结果表明宫颈鳞癌、宫颈息肉及慢性宫颈炎的发病与HSV-2关系密切,但因果关系尚需进一步研究.

关键词: 单纯疱疹病毒, 宫颈鳞癌, 宫颈息肉, 慢性宫颈炎, 免疫细胞化学

Abstract: Herpes simplex virus type 2(HSV-2)in cervical biopsy was determined by using im-munocytochemical technique in 42 cases with different cervical diseases.The results showed that there were the high frequence of positive immunoreaction in the squamous cell carcino-ma of cervix(88.9%),cervical polyps(77.8%)and chronic cervicitis(68.4%).On the other hand,all 5 cases with cervical adenocarcinoma and adenocarcinoma of endometrium invading the cervix were negative.This indicates that the pathological courses of squamons cell carci-noma of cervix,cervical polyps and chronic cervicitis have close correlation with the infection of HSV-2.Further study is needed for understanding the causality of those diseases and in-fection of HSV-2.

Key words: herps simplex virus, squamons cell carcinoma of cervix, cervical polyp, chronic cervicitis, immunocytochemistry

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