唾液腺组织中HBsAg和HBcAg分布的探讨

首都医科大学学报 ›› 1994, Vol. 15 ›› Issue (4): 299-301.

唾液腺组织中HBsAg和HBcAg分布的探讨

杨静娴¹, 郎振为², 杨大海¹, 翟素珍¹, 王凤光¹

1. 首都医学院附属北京口腔医院;2. 北京佑安医院

收稿日期:1993-10-08 修回日期:1900-01-01 出版日期:1994-10-15 发布日期:1994-10-15

The Study of HBsAg and HBcAg Distribution in Salivary Gland Tissue

Yang Jingxian¹, Lang Zhenwei², Yang Dahai¹, Zhai Suzhen¹, Wang Fengguang¹

Beijing Stomatological Hospital, Capital Institute of Medicine

Received:1993-10-08 Revised:1900-01-01 Online:1994-10-15 Published:1994-10-15

摘要/Abstract

摘要： 应用多克隆抗体和卵白素-生物素-辣根过氧化物酶复合物法(ABC法)对13例乙型肝炎患者手术摘除的唾液腺组织中HBsAg和HBcAg进行检测.结果HBsAs阳性4例,HbsAg和HBcAg阳性1例.对照组6例,测得HBsAg阳性1例.本实验结果首次为乙型肝炎患者唾液腺组织内HBBV的分布提供了形态学依据,表明乙型肝炎患者唾液中的HBV源于受感染的唾液腺组织.

关键词: 免疫组织化学法, 乙型肝炎病毒表面抗原, 乙型肝炎病毒核心抗原, 唾液腺

Abstract: In this study,the extirpated parotid,submandibular and sublingual gland from 13 cases of hepatitis B were determinated with polyclonal antibody and antibiotin-biotinhorse radish peroxidase(ABC), 4 cases were HBsAg(+),1 case was HBsAg(+)and HBcAg(+). The results provided morphologic basis for HBV distribution in salivary gland of hepatitis B,and showed that HBV in the saliva of hepatitis patients originated from infections salivary gland tissue.

Key words: immunohistochemical method, HBsAg, HBcAg, salivary gland

中图分类号:

杨静娴;郎振为;杨大海;翟素珍;王凤光. 唾液腺组织中HBsAg和HBcAg分布的探讨[J]. 首都医科大学学报, 1994, 15(4): 299-301.

Yang Jingxian;Lang Zhenwei;Yang Dahai;Zhai Suzhen;Wang Fengguang. The Study of HBsAg and HBcAg Distribution in Salivary Gland Tissue[J]. Journal of Capital Medical University, 1994, 15(4): 299-301.