青霉素G皮试液稳定性研究

首都医科大学学报 ›› 1995, Vol. 16 ›› Issue (2): 117-118.

青霉素G皮试液稳定性研究

姜雄平¹, 于文胜¹, 魏立平¹, 孙颂三²

1. 首都医学院药理学教研室;2. 首都医学院药理学教研室

收稿日期:1994-12-30 修回日期:1900-01-01 出版日期:1995-04-15 发布日期:1995-04-15

Stability of Penicilin G Skin Allergy Test Solution

Jiang Xiongping¹, Yu Wensheng¹, Wei Liping¹, Sun Songsan²

1. Drug Control Institute of PLA;2. Department of Pharmacology, Capital Institute of Medicine

Received:1994-12-30 Revised:1900-01-01 Online:1995-04-15 Published:1995-04-15

摘要/Abstract

摘要： 以高效液相色谱法测定青霉素G皮试液及浓储备液在低温下的稳定性,结果表明:青霉素G稀溶液较浓溶液稳定,溶液的pH值随放置时间的延长而降低,青霉素G的降解速率随pH的降低而加速。

关键词: 高效液相色谱法, 青霉素G, 过敏试验

Abstract: The stability of penicillin Gskin allergy test solution and penicillin Gconcentrated solution stored at low temperature was determined by RP-HPLC.The results showed that penicillin G was much more stable in dilute solution than in concentrated solution,and that the pHvalues decreased with the lapse of time,and that degradation rate of penicillin G in solution increased with decrease of pH.

Key words: HPLC, penicillin G, allergy test

中图分类号:

R927.11

姜雄平;于文胜;魏立平;孙颂三. 青霉素G皮试液稳定性研究[J]. 首都医科大学学报, 1995, 16(2): 117-118.

Jiang Xiongping;Yu Wensheng;Wei Liping;Sun Songsan. Stability of Penicilin G Skin Allergy Test Solution[J]. Journal of Capital Medical University, 1995, 16(2): 117-118.

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