肥胖儿童脂质和糖代谢的研究

首都医科大学学报 ›› 1997, Vol. 18 ›› Issue (1): 45-47.

肥胖儿童脂质和糖代谢的研究

华琦¹, 何士大¹, 王育琴²

1. 首都医科大学宣武医院心血管内科;2. 首都医科大学宣武医院心血管儿科

收稿日期:1996-01-20 修回日期:1900-01-01 出版日期:1997-01-15 发布日期:1997-01-15

Studies on Serum Lipoprotein Lipids and Apolipoproteins and Insulin Secretion in Simple Obese Children

Hua Qi¹, He Shida¹, Wang Yuqin²

Xuanwu Hospital, Affiliate of Capital University of Medical Sciences

Received:1996-01-20 Revised:1900-01-01 Online:1997-01-15 Published:1997-01-15

摘要/Abstract

摘要： 应用多种方法从不同角度观察27例8～12岁单纯肥胖症儿童及18例同龄健康儿童的脂质代谢及糖代谢。发现肥胖儿组的总胆固醇、甘油三酯、氧化型低密度脂蛋白及载脂蛋白B均较对照组明显升高(P<0.05～0.001),载脂蛋白A降低(P<0.05),脂蛋白(a)无明显变化,C肽及胰岛素较对照组明显升高(P<0.05及0.001).腹部B超检查显示肥胖儿童组脂肪肝发生率占92.6%(P<0.05).本研究提示儿童期单纯肥胖症的脂质代谢及糖代谢均有异常改变,必须及早引起重视。

关键词: 单纯肥胖症, 脂质代谢, 糖代谢

Abstract: To study the initial period of fat deposition in human obesity,27 children of over 120% ideal body weight aged 8～12 years old and 18 children of ideal body weight in the same age were observed.It was found that TC,TG,Ox-LDL and apoBwere markedly higher and apoA lower in obese children group than in control group (P<0.05～0.001),there were no difference between two groups in Lp(a).Abdominal ulfrasonic examination showed that 92.6% obese children had fatty liver.It was also found that peptide Cand insulin were higher in obese children group than in control group (P<0.05 and 0.001),and on positive correlation existed between peptide Cand body weight and between insulin and body weight.The investigation results suggested that there were abnormal metabolism of fatty and glycerol in simple obese children.

Key words: simple obese children, lipoprotein lipids, glycerol

中图分类号:

R151.1

华琦;何士大;王育琴. 肥胖儿童脂质和糖代谢的研究[J]. 首都医科大学学报, 1997, 18(1): 45-47.

Hua Qi;He Shida;Wang Yuqin. Studies on Serum Lipoprotein Lipids and Apolipoproteins and Insulin Secretion in Simple Obese Children[J]. Journal of Capital Medical University, 1997, 18(1): 45-47.

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