首都医科大学学报 ›› 1997, Vol. 18 ›› Issue (4): 317-320.

• 论著 • 上一篇    下一篇

氡子体致肺癌作用及与其他暴露因素间作用形式的研究

于石成1, 倪宗瓒2, 姚树祥3, 乔友林4, Philip R. Taylor4   

  1. 1. 首都医科大学预防医学系卫生统计教研室;2. 华西医科大学公共卫生学院;3. 云南锡业公司劳动防护研究所;4. 美国国立癌症研究所
  • 收稿日期:1996-10-16 修回日期:1900-01-01 出版日期:1997-10-15 发布日期:2013-10-28

A Study on Radon and Lung Cancer Risk and Patterns of Interaction with Other Carcinogens

Yu Shicheng1, Ni Zongzan2, Yao Shuxiang3, Qiao Youlin4, Philip R. Taylor4   

  1. 1. Department of Health Statistics, Faculty of Preventive Medicine, Capital University of Medical Sciences;2. West China University of Medical Sciences;3. Yunnan Tin Corbnration;4. National Cancer Institute U.S.A
  • Received:1996-10-16 Revised:1900-01-01 Online:1997-10-15 Published:2013-10-28

摘要: 应用前瞻性队列研究方法,对云锡高危人群氡子体致肺癌作用及与其他暴露因素间作用形式进行了探讨。结果表明:调整年龄、粉尘或砷暴露后 随累积氡子体暴露量(WLM)增大、暴露年限越长、首次氡子体暴露年龄越小患肺癌的危险性越大。结果支持氡子体是云锡矿工肺癌病因因素的假说。分析没有发现氡子体与吸烟、粉尘、砷暴露、慢性支气管炎史之间有相乘的交互作用。

关键词: 肺癌, 氡子体, 交互作用, Poison回归模型

Abstract: A prospective cohort study of the high-risk population among miners and smelters in Yunnan Tin Corporation was done from 1992 to the end of 1994. The results showed that the risk of lung cancer increased with accumulated radon decay products(WLM) exposure years of radon first radon progeny age attained. The study supported that radon progeny is a lung carcinogen among miners in YTC. There is no interactions between radon progeny and smoking chronic bronchitis dust exposure arsenic exposure in the analyses. The patterns of interaction should be evaluated in future.

Key words: lung cancer, radon decay products, interaction, Poisson regression model

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