辛伐他丁与洛伐他丁调节血脂作用的比较

首都医科大学学报 ›› 1998, Vol. 19 ›› Issue (1): 49-50.

辛伐他丁与洛伐他丁调节血脂作用的比较

高国静, 华琦

首都医科大学宣武医院内科

收稿日期:1997-09-22 修回日期:1900-01-01 出版日期:1998-01-15 发布日期:1998-01-15

Contrast between Simvastatin and Lovastatin in Treatment of Patients with Hyperlipoproteins

Gao Guojing, Hua Qi

Internal Medicine, Xuanwu Hospital, Affiliate of Capital University of Medical Sciences

Received:1997-09-22 Revised:1900-01-01 Online:1998-01-15 Published:1998-01-15

摘要/Abstract

摘要： 分别用辛伐他丁(5mg)、洛伐他丁(20mg)治疗经饮食控制无效的高胆固醇血症患者各20例.于服药前、服药4周及8～12周时检测血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)水平.发现辛伐他丁与洛伐他丁均能显着降低血清TC及LDL-C,升高HDL-C.辛伐他丁与洛伐他丁降低TC的作用接近,而降低LDL-C与升高HDL-C的作用前者优于后者.

关键词: 辛伐他丁, 洛伐他丁, 高胆固醇血症

Abstract: Forty patients with hypercholesterolemia were divided into two subgroups, twenty of them were treated with simvastatin 5 mg qn, and twenty of them were treated with lovastatin 20 mg qn. The results showed that after complete 8～12 weeks of therapy, total cholesterol and low density lipoprotein decreased and high density lipoprotein increased in both grorps, simvastatin was more efficacious than lovastatin.

Key words: simvastatin, lovastatin, hypercholesterolemia

中图分类号:

R589.2

高国静;华琦. 辛伐他丁与洛伐他丁调节血脂作用的比较[J]. 首都医科大学学报, 1998, 19(1): 49-50.

Gao Guojing;Hua Qi. Contrast between Simvastatin and Lovastatin in Treatment of Patients with Hyperlipoproteins[J]. Journal of Capital Medical University, 1998, 19(1): 49-50.

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