Imx 系统连续监测肝癌及慢性肝炎患者血清甲胎蛋白的变化

首都医科大学学报 ›› 1998, Vol. 19 ›› Issue (1): 51-53.

Imx 系统连续监测肝癌及慢性肝炎患者血清甲胎蛋白的变化

孔淑玲, 闵福援, 王少祥

北京佑安医院中心实验室

收稿日期:1997-03-26 修回日期:1900-01-01 出版日期:1998-01-15 发布日期:1998-01-15

Measurement of Serum Alphafetoprotein in Patients with Primary Hepatocellular Carcinoma and Chronic Active Hepatitis by Immunoassay System Imx

Kong Shuling, Min Fuyuan, Wang Shaoxiang

Beijing Youan Hospital

Received:1997-03-26 Revised:1900-01-01 Online:1998-01-15 Published:1998-01-15

摘要/Abstract

摘要： 采用全自动免疫分析系统(Imx),对原发性肝癌(PHC)、慢性活动性肝炎(CAH)患者的血清甲胎蛋白(AFP)含量进行观察.结果:PHC患者血清AFP含量的异常率为75%(66/88),CAH患者的异常率为21.8%(22/101).并对11例PHC患者进行了手术前后AFP含量的动态观察,对15例CAH患者进行了AFP含量连续监测.发现:PHC患者术后AFP持续增高者预后不良;CAH患者AFP持续增高有癌变的可能.提示:AFP含量的变化与PHC和CAH的病程变化和预后相吻合.

关键词: 全自动免疫分析系统(Imx), 原发性肝癌, 慢性活动性肝炎

Abstract: Using fully automated immunoassay system Imx, the serum alpha fetoprotein(AFP)levels in patients with primary hepatocellular carcinoma(PHC)and chronic active hepatitis(CAH)were quantitatively determined. Results: In 75% of patients with PHC, the serum AFP levels were unnormal. In 11 patients, before and after operation, the serum AFP levels were observed dynamically. The serum AFP levels were elevated in 21.8% of 110 patients with CAH. In 13 of 15 cases, the serum AFP levels were from 14.27 nmol/L to normal. In another 2 cases, the serum AFP levels were persistently high, denoting a poor prognoses. Changes in contents of AFP coincided with changes of disease course and prognosis of PHC and CAH.

Key words: primary hepatocellular carcinoma, chronic active hepatitis, immunoassay system Imx

中图分类号:

孔淑玲;闵福援;王少祥. Imx 系统连续监测肝癌及慢性肝炎患者血清甲胎蛋白的变化[J]. 首都医科大学学报, 1998, 19(1): 51-53.

Kong Shuling;Min Fuyuan;Wang Shaoxiang. Measurement of Serum Alphafetoprotein in Patients with Primary Hepatocellular Carcinoma and Chronic Active Hepatitis by Immunoassay System Imx[J]. Journal of Capital Medical University, 1998, 19(1): 51-53.