国产洛伐他汀治疗原发性高胆固醇血症临床观察

首都医科大学学报 ›› 1998, Vol. 19 ›› Issue (4): 339-341.

国产洛伐他汀治疗原发性高胆固醇血症临床观察

张彤, 杜凤和, 张剑峰

首都医科大学附属北京天坛医院心内科

收稿日期:1997-12-21 修回日期:1900-01-01 出版日期:1998-10-15 发布日期:1998-10-15

The Effect of Chinese Lovastatin on Essential Hypercholesterolemia

Zhang Tong, Du Fenghe, Zhang Jianfeng

Department of Cardiology, Beijing Tiantan Hospital, Affiliate of Capital University of Medical Sciences

Received:1997-12-21 Revised:1900-01-01 Online:1998-10-15 Published:1998-10-15

摘要/Abstract

摘要： 采用随机双盲对照实验,观察了国产洛伐他汀(lovastatin)治疗原发性高胆固醇血症的效果.结果:服国产洛伐他汀第1、2个月血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)较治疗前明显下降(P<0.01),与美国产洛伐他汀比较作用无显着差异(P>0.05),2组副作用均较轻.结果提示国产洛伐他汀治疗原发性高胆固醇血症疗效可靠,与美国产同类产品疗效相当.

关键词: 原发性高胆固醇血症, 洛伐他汀, 治疗结果

Abstract: Fifty-eight patients with essential hypercholesterolemia(TC≥5.98 mmol/L)were treated with Chinese lovastatin and American lovastatin(MSD)by means of randomized double blind placebo-controlled clinical trials. The results showed that Chinese lovastatin decreased TC, LDL-C in the same manner as American lovastatin(MSD)within 1～2 month. Both of them had mild side-effects.

Key words: hypercholesterolemia, lovastatin, effect of treatment

中图分类号:

R589.2

张彤;杜凤和;张剑峰. 国产洛伐他汀治疗原发性高胆固醇血症临床观察[J]. 首都医科大学学报, 1998, 19(4): 339-341.

Zhang Tong;Du Fenghe;Zhang Jianfeng . The Effect of Chinese Lovastatin on Essential Hypercholesterolemia[J]. Journal of Capital Medical University, 1998, 19(4): 339-341.

[1]	曹富雨, 季长高. 术后快速康复对全膝关节置换术后功能的影响[J]. 首都医科大学学报, 2023, 44(1): 167-171.
[2]	罗巍;吴尊友;卫晓丽;贾伟;张群财;李亮亮;颜鸿. 美沙酮维持治疗结果的影响因素研究[J]. 首都医科大学学报, 2007, 28(3): 373-377.