脑动静脉畸形手术前后局部脑皮质血流的变化

首都医科大学学报 ›› 2004, Vol. 25 ›› Issue (2): 201-204.

脑动静脉畸形手术前后局部脑皮质血流的变化

石广志¹, 赵继宗², 王硕², 王永刚², 陆铮²

1. 首都医科大学附属北京天坛医院ICU病房;2. 首都医科大学附属北京天坛医院神经外科

收稿日期:2003-12-19 修回日期:1900-01-01 出版日期:2004-04-15 发布日期:2004-04-15

Changes of Regional Cerebral Blood Flow after Resection of Cerebral Arteriovenous Malformation

Shi Guangzhi¹, Zhao Jizong², Wang Shuo², Wang Yonggang², Lu Zheng²

1. Department of ICU, Beijing Tiantan Hospital, Affiliate of Capital University of Medical Sciences;2. Department of Neurosurgery, Beijing Tiantan Hospital, Affiliate of Capital University of Medical

Received:2003-12-19 Revised:1900-01-01 Online:2004-04-15 Published:2004-04-15

摘要/Abstract

摘要： 为观察脑动静脉畸形手术前后局部脑皮质血流量(CBF)的变化,对63例成年脑血管畸形病人:25例巨大脑血管畸形(血管畸形直径≥6cm),38例小血管畸形(血管畸形直径<6cm)进行研究。用激光多普勒血流仪(LDF)分别记录血管畸形切除前后及术后24h脑血流数值,比较脑血流变化情况。发现:巨大血管畸形切除后脑血流比切除前明显增加,直到术后24h仍然保持在高水平;而小血管畸形切除后脑血流无显著变化。提示:巨大血管畸形和小血管畸形在切除前后的脑血流变化是不同的,监测脑血管畸形切除后脑血流变化有助于减少巨大血管畸形的出血等并发症。

关键词: 颅内动静脉畸形, 局部血流, 手术

Abstract: The aim was to investigate pre-and postoperative change of regional cerebral cortical blood flow in patients with cerebral arteriovenous malformation (AVM). Sixty-three adult patients with AVM were entered into this study at Beijing TianTan Hospital from September 2001 to May 2003. One group had 25 patients who had giant cerebral AVM (diameter more than 6 cm) and the other group had 38 patients who had small AVM (diameter less than 6 cm). Pre and post AVM resections Cortical blood flow(CBF) were measured by laser Doppler flowmeter(LDF), Post-operatively, the probe of LDF was implanted adjacent to the area of the AVM for 24 h and the CBF was recorded. The CBF in the giant group increased obviously, and still remained at high level till 24 h after resection. In small AVM group, the CBF had no obvious change. The change of the CBF in giant and small AVM during the operation is different. Monitoring the CBF is helpful to understand preand postoperative change of cerebral cortical blood flow in patients with cerebral arteriovenous malformation.

Key words: intracranial arteriovenous malformation, regional blood flow, intraoperative

中图分类号:

R743.4

石广志;赵继宗;王硕;王永刚;陆铮. 脑动静脉畸形手术前后局部脑皮质血流的变化[J]. 首都医科大学学报, 2004, 25(2): 201-204.

Shi Guangzhi;Zhao Jizong;Wang Shuo;Wang Yonggang;Lu Zheng. Changes of Regional Cerebral Blood Flow after Resection of Cerebral Arteriovenous Malformation[J]. Journal of Capital Medical University, 2004, 25(2): 201-204.

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