首都医科大学学报 ›› 2009, Vol. 30 ›› Issue (2): 154-160.

• 肾病学专题 • 上一篇    下一篇

血液透析滤过在维持性透析患者中的临床应用

尹道馨, 张东亮, 刘文虎   

  1. 首都医科大学附属北京友谊医院肾病内科
  • 收稿日期:2009-01-18 修回日期:1900-01-01 出版日期:2009-04-21 发布日期:2009-04-21
  • 通讯作者: 刘文虎

Clinical Aspects of Hemodiafiltration on Patients with Maintain Renal Replacement Therapy

YIN Dao-xin, ZHANG Dong-liang, LIU Wen-hu   

  1. Department of Nephrology, Beijing Friendship Hospital, Capital Medical University
  • Received:2009-01-18 Revised:1900-01-01 Online:2009-04-21 Published:2009-04-21

摘要: 血液透析滤过(hemodiafiltration,HDF)结合了血液透析(hemodialysis,HD)和血液滤过(hemofiltration,HF)的特点,可以有效地清除血液中中小分子毒素,减轻炎性反应状态,维持透析中血流动力学稳定,改善终末期肾脏病患者贫血、钙磷代谢紊乱、营养状态等症状。近年来大型的观察性研究显示HDF可以降低终末期肾脏病患者的死亡风险。本文综述了HDF在维持性透析患者中的临床应用及近期进行的大型观察性或随机对照试验的结果。

关键词: 血液透析滤过, 在线血液透析滤过, 血液透析, 生存率

Abstract: Hemodiafiltration(HDF) is an extracorporeal renal-replacement technique using a highly permeable membrane, in which diffusion and convection are combined to enhance solute removal in a wide spectrum of molecular weights. HDF can improve clinical conditions and reduce morbidity compared with conventional hemodialysis. In this review, it summarizes recent views about clinical aspects of HDF, the main observational studies and ongoing randomized-controlled trials.

Key words: hemodiafiltration, on-line hemodiafiltration, hemodialysis, survival rate

中图分类号: