2型糖尿病患者听力损失的影响因素及其与眼底病变相关性

doi:10.3969/j.issn.1006-7795.2019.01.005

首都医科大学学报 ›› 2019, Vol. 40 ›› Issue (1): 20-26.doi: 10.3969/j.issn.1006-7795.2019.01.005

• 糖尿病慢性合并症-听力损失与平衡障碍研究 • 上一篇下一篇

2型糖尿病患者听力损失的影响因素及其与眼底病变相关性

王鹏¹, 刘博², 赵明月³, 杨毅⁴

1. 首都医科大学附属复兴医院综合科, 北京 100038;
2. 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科北京市耳鼻咽喉科研究所, 北京 100730;
3. 北京航天总医院干部医疗科, 北京 100076;
4. 首都医科大学附属北京同仁医院内分泌科, 北京 100730

收稿日期:2018-12-06 出版日期:2019-01-21 发布日期:2019-01-23
通讯作者: 杨毅 E-mail:yangyi302tr@126.com
基金资助:
首都卫生发展科研专项（首发重点2018-1-1091）。

Influencing factors of hearing loss and its correlation with retinopathy in type 2 diabetes mellitus patients

Wang Peng¹, Liu Bo², Zhao Mingyue³, Yang Yi⁴

1. Integrated Department, Fuxing Hospital, Capital Medical University, Beijing 100038, China;
2. Department of Otorhinolaryngology, Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Otorhinolaryngology, Beijing 100730, China;
3. Department of Cadre Medical, Beijing Airospace General Hospital, Beijing 100076, China;
4. Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China

Received:2018-12-06 Online:2019-01-21 Published:2019-01-23
Supported by:
This study was supported by Capital Health Research and Development of Special(2018-1-1091).

摘要/Abstract

摘要： 目的探讨2型糖尿病患者眼底病变（diabetic retinopathy，DR）与听力损害相关性，探讨2型糖尿病听力损害的相关危险因素。方法以2013年10月至2014年12月首都医科大学附属北京同仁医院内分泌科就诊的糖尿病患者73例为观察对象。询问相关病史，有无主观耳科症状，进行糖尿病眼底检查，纯音听力测定、声导抗检查。同时完善血糖、血压、血脂等检查。依照糖尿病眼底病变、听力损失情况进行分组，对比检查指标有无统计学差异。结果听力损失组与正常组比较，年龄（P=0.005）、DR（P=0.006）增加，高频听力受损组与正常组比较，年龄（P=0.001）、DR（P=0.017）增加。Logistic回归分析结果显示，DR对平均听力受损有影响（OR=6.499，95%CI：1.546~27.317，P=0.011），对高频听力受损有影响（OR=6.763，95%CI：1.285~35.580，P=0.024）。结论糖尿病听力损失与DR有关，可无自觉症状。发现DR的患者应积极进行听力筛查，以便早期发现听力损害及时干预。

关键词: 糖尿病, 糖尿病视网膜病变, 听力损害

Abstract: Objective To analyze the association between diabetic retinopathy(DR) and hearing loss in diabetes mellitus(DM) patients and to investigate the factors which affect hearing among DM patients. Methods Questionnaires and pure tone audiometry were performed in 73 patients with type 2 DM, The average age was (53.0±8.4)years,the course of diabetes was (10.3±7.0) years, who visited Beijing Tongren Hospital, Capital Medical University from October 2013 to December 2014. The patients were categorized into groups according to hearing loss and DR.The examination of the ocular fundus, the pure tone air and bone conduction threshold testing,Hemoglobin A, blood pressure, lipid and other examinations were carried out. Results In all of the 73 subjects with diabetes, pure tone audiometry confirmed the incidence of hearing loss in 26.0%, including10.5% cases who did not complained of hearing loss. The incidence of retinopathy is 39.7%. The age (P=0.005) and DR (P=0.006) exacerbated hearing loss in the mean hearing loss group of diabetes mellitus compared with the normal group. It is the same in the high-frequency hearing loss group compared with the normal group, with the age (P=0.001) and DR (P=0.017). Logistic regression analysis showed that the DR(OR=6.499,95%CI:1.546-27.317,P=0.011) significantly exacerbated the hearing loss in the both average hearing loss and high frequency hearing loss DR (OR=4.448,95%CI:1.195-16.551,P=0.026). Conclusion There have significantly association between DR and hearing loss in DM patients. The patient's subjective feeling did not reflect exactly their hearing function. The hearing screening should be performed in time for the patients with DR.

Key words: diabetes mellitus, diabetic retinopathy, hearing loss

中图分类号:

R587.1

王鹏, 刘博, 赵明月, 杨毅. 2型糖尿病患者听力损失的影响因素及其与眼底病变相关性[J]. 首都医科大学学报, 2019, 40(1): 20-26.

Wang Peng, Liu Bo, Zhao Mingyue, Yang Yi. Influencing factors of hearing loss and its correlation with retinopathy in type 2 diabetes mellitus patients[J]. Journal of Capital Medical University, 2019, 40(1): 20-26.

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2型糖尿病患者听力损失的影响因素及其与眼底病变相关性

Influencing factors of hearing loss and its correlation with retinopathy in type 2 diabetes mellitus patients

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