关键词: 异丙酚, 球后神经阻滞, 血流动力学

Abstract:

Objective To investigate hemodynamics of elderly patients with propofol application before retrobulbar nerve block in department of ophthalmology. Methods There were 40 patients in department of ophthalmology to be operated, age≥65 years, ASA Ⅱ～Ⅲ grade. They were randomly allocated into A and B two groups. A was control group(n=20), B was propofol group(n=20). The patients of A group were routinely operated with retrobulbar nerve block without general anaesthetic. The patients of B group were injected propofol (0.4 mg/kg). Heart rate, blood pressure and SpO₂ of patients were in two groups in peri-operational period. Results Heart rate, systolic pressure and diastolic pressure increased significantly observed in patients of A group 1 minute after nerve block(P<0.05). They gradually returned to basic level after 2～5 min. Heart rate, systolic pressure and diastolic pressure did not change much in patients of B group every time points. There are significantly statistical difference between patients of A group and patients of B group in heart rate, systolic pressure and diastolic pressure 1 min after nerve block( P< 0.05). Conclusion Injecting propofol(0.4 mg/kg) into retrobulbar nerve block for elderly patients is advantageous in terms of qick effect, well sedation, stable hemodynamics, and less respiration disturbance.

Key words: propofol, retrobulbar nerve block, hemodynamics