消痔灵双层4步注射治疗完全性直肠脱垂临床疗效评价

首都医科大学学报 ›› 2006, Vol. 27 ›› Issue (6): 812-815.

消痔灵双层4步注射治疗完全性直肠脱垂临床疗效评价

李华山¹, 李国栋¹, 李东冰², 王春晓³, 王晓锋¹, 景建中¹, 寇玉明¹, 张建华⁴, 胡占岭³

1. 中国中医科学院广安门医院;2. 中国中医科学院西苑医院;3. 沈阳市肛肠医院;4. 山西临汾市骨科医院

收稿日期:2006-06-16 修回日期:1900-01-01 出版日期:2006-12-24 发布日期:2006-12-24

Evaluation of Curative Effect of Xiaozhiling Injection Double-layer Four-step Inject therapy of Full Thickness Rectal Prolapse

Li Huashan¹, Li Guodong¹, Li Dongbing², Wang Chunxiao³, Wang Xiaofeng¹, Jing Jianzhong¹, Kou Yuming¹, Zhang Jianhua⁴, Hu Zhanling³

1. Guang An Men Hospital, China Academy of Traditional Chinese Medicine Science;2. Xi Yuan Hospital, China Academy of Traditional Chinese Medicine Science;3. Shen Yang Rectum Hospital;4. Linfen Orthopaedics Hospital of Shan Xi

Received:2006-06-16 Revised:1900-01-01 Online:2006-12-24 Published:2006-12-24

摘要/Abstract

摘要：

目的客观评价消痔灵双层4步注射治疗完全性直肠脱垂的临床疗效与安全性.方法将36例患者随机分为A、B 2组,A组20例为高浓度组;B组16例为低浓度组,采取双层4步注射疗法.以直肠脱垂长度、排粪造影结果作为疗效性指标,患者一般情况、全血细胞分析、肝肾功能检查作为安全性指标.并进行3个月1次的随访.结果 A组临床控制19例,有效1例;B组临床控制16例.两组近期疗效未见显著差异,均未见严重肝肾功能损害,经3至36个月随访,复发7例.复发病例中有4例经再次注射而达到临床控制,1例行开腹作肠管切除术,1例行开腹直肠悬吊固定术,1例行PPH手术.结论该疗法痛苦小,疗效较好,操作简便,费用低廉,且可重复使用,可作为完全性直肠脱垂的首选治疗方法,适宜于基层医院推广应用.

关键词: 消痔灵注射液, 双层4步注射法, 直肠脱垂, 疗效评价

Abstract:

Objective To evaluate the clinical curative effect and security of therapy of Xiaozhiling injection of complete rectal prolapse.Methods 36 patients that were randomly divided into group A and B were taken double-layer four-step inject therapy.A was group of high concentration with 20 patients,and B was group of low concentration with 16 patients.The length of rectal prolapse and radiography of defecation were the indicators of curative effect,and the indicators of security were the general conditions of patients,the blood cell analysis and the function of liver and kidney.Follow-ups were taken every three months.Results In group A,19 patients were clinical controlled and 1 case was effective.In group B,16 patients were clinical controlled.There was no statistically significant effect between the two groups(P> 0.05),liver and kidney function had no serious damage.After 3³6 months' follow-up,7 cases recurred.Of the 7 patients,4 were clinical controlled after the second time injection,1 was taken intestine resection,1 was taken Sling fixation of rectum,1 was taken PPH.Conclusion The therapy is painless,effective,simple,low-cost and repeatable.Which is appropriate for being generalized in the grass roots hospitals as preferred method.

Key words: Xiaozhiling injection, double-layer four-step inject therapy, rectal prolapse, evaluation of curative effect

中图分类号:

R266

李华山;李国栋;李东冰;王春晓;王晓锋;景建中;寇玉明;张建华;胡占岭. 消痔灵双层4步注射治疗完全性直肠脱垂临床疗效评价[J]. 首都医科大学学报, 2006, 27(6): 812-815.

Li Huashan;Li Guodong;Li Dongbing;Wang Chunxiao;Wang Xiaofeng;Jing Jianzhong;Kou Yuming;Zhang Jianhua;Hu Zhanling. Evaluation of Curative Effect of Xiaozhiling Injection Double-layer Four-step Inject therapy of Full Thickness Rectal Prolapse[J]. Journal of Capital Medical University, 2006, 27(6): 812-815.