2230例变应性疾病患者血清特异性抗体测定分析

doi:10.3969/j.issn.1006-7795.2011.05.017

首都医科大学学报 ›› 2011, Vol. 32 ›› Issue (5): 667-669.doi: 10.3969/j.issn.1006-7795.2011.05.017

2230例变应性疾病患者血清特异性抗体测定分析

赵鸿芬, 李小霞, 赵京莉

首都医科大学宣武医院风湿变态科,北京 100053

收稿日期:2011-02-23 修回日期:1900-01-01 出版日期:2011-10-21 发布日期:2011-10-21
通讯作者: 李小霞

Analysis of serum specific IgE in 2 230 patients with allergic diseases

ZHAO Hong-fen, LI Xiao-xia, ZHAO Jing-li

Department of Allergy and Rheumatology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China

Received:2011-02-23 Revised:1900-01-01 Online:2011-10-21 Published:2011-10-21

摘要/Abstract

摘要： 目的检测变应性疾病血清特异性抗体筛选相关过敏原,为临床诊断和治疗提供依据。方法采用过敏原检测系统,对2 230例变应性疾病患者的血清特异性免疫球蛋白E(immunoglobulin,IgE)及总IgE水平进行了检测。结果 2 230例变应性疾病患者中过敏原以屋尘螨(28.3%)、粉尘螨(26.6%)为最高,其后依次为蒿(14.9%)、猫毛皮屑(9%)、牛羊肉(9%)、蟑螂(8.3%)、鱼虾蟹(8.1%)、霉菌(6.6%)、牛奶(6.1%)、矮豚草(5.6%)、腰果花生(4.6%)、榆、梧桐、柳、三角叶杨(3.8%)、鸡蛋白(3.8%)、黄豆(3.1%);总IgE阳性率为46.9%。结论血清特异性IgE及总IgE的检测分析可以帮助临床寻找相应过敏原,为变应性疾病的预防、诊断和治疗提供依据。

关键词: 变应性疾病, 过敏原, 免疫球蛋白E

Abstract: Objective To detect serum specific IgE in allergic diseases for clinical diagnosis and therapy. Methods The serum specific IgE and total IgE(sIgE) were detected by enzyme immunoassay in 2 230 patients. Results The dermatophagoides farinae(28.3%) and pteronyssinus(26.6%) were the most common allergen in 2 230 patients, followed by Artemisia(14.9%), cat hair dander(9%), beef and mutton(9%), cockroaches(8.3%), seafood(8.1%), fungi(6.6%), milk(6.1%), short ragweed(5.6%), peanuts, cashew nuts(4.6%), elm, sycamore, willow, cottonwood(3.8%), egg white(3.8%), soybeans(3.1%). The positive rate of total IgE was 46.9%. Conclusion The detection of serum specific IgE and total IgE can help to find the corresponding clinical allergy, and provide evidences for prevention, diagnosis and therapy of allergic diseases.

Key words: allergic diseases, allergens, immunoglobulin E

中图分类号:

R 392.8

赵鸿芬;李小霞;赵京莉. 2230例变应性疾病患者血清特异性抗体测定分析[J]. 首都医科大学学报, 2011, 32(5): 667-669.

ZHAO Hong-fen;LI Xiao-xia;ZHAO Jing-li. Analysis of serum specific IgE in 2 230 patients with allergic diseases[J]. Journal of Capital Medical University, 2011, 32(5): 667-669.

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2230例变应性疾病患者血清特异性抗体测定分析

Analysis of serum specific IgE in 2 230 patients with allergic diseases

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