首都医科大学学报 ›› 1986, Vol. 7 ›› Issue (4): 264-267,332,333.

• 论著 • 上一篇    下一篇

α,α′-联硫二[β-(2-呋喃)丙烯酸]的制备及其对大鼠血清锌含量的影响

张英侠, 曾昭晖, 达志坚   

  1. 北京第二医学院化学教研室
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1986-10-15 发布日期:1986-10-15

Preparation of α,α'-dithiobis [β-(2-furan)acrylic acid] and its Influence on the Serum Zinc Levels in Rats

Zhang Yinxia   

  1. Department of Chemistry
  • Received:1900-01-01 Revised:1900-01-01 Online:1986-10-15 Published:1986-10-15

摘要:

本文提出用糠醛和绕丹宁(rhodanine)为原料制备α,α′-联硫二[β-(2-呋喃)丙烯酸]的方法,并研究其对大鼠给予硫酸锌后血清锌含量的影响。结果证明能提高大鼠血清锌含量5—6倍。

Abstract:

In the present investigation,the preparation of α,α-dithiobis-[β-(2-furan)aerylic acid](DTFA)from furaldehyde and rhodanine and its effect on serum zinc concentration were studied in rats.By usingatomic absorption method serum zinc concentration was determined afteradministration of ZnSO4 or mixture of ZnSO4 and DTFA.It was shownthat the serum zinc level in rats after the administration of mixtureZnSO4 and DTFA was much higher and long-lasting than that in ratfollowing a simple treatment with ZnSO4.