首都医科大学学报 ›› 2000, Vol. 21 ›› Issue (2): 155-156.

• 论著 • 上一篇    下一篇

米索前列醇在足月妊娠引产中的应用

冯玲, 赵莲   

  1. 首都医科大学附属北京同仁医院妇产科
  • 收稿日期:1999-10-22 修回日期:1900-01-01 出版日期:2000-04-15 发布日期:2000-04-15

Application of Misoprostol for Cervical Ripening and Labor Induction

Feng Ling, Zhao Lian   

  1. Department of Obstetrics and Gynecology, Beijing Tongren Hospital, Affiliate of Capital University of Medical Sciences
  • Received:1999-10-22 Revised:1900-01-01 Online:2000-04-15 Published:2000-04-15

摘要: 为观察米索前列醇用于足月妊娠引产的效果,对有引产指征、无药物禁忌证的足月单胎头位、无宫缩的孕妇91例分别行米索前列醇引产(米索组,49例)和静推地西泮后静点缩宫素引产(对照组,42例).结果显示米索组用药后宫颈评分平均提高2.69分,对照组提高1.80分,差异有显着性(P<0.05).米索组引产的有效率为93.88%,显着高于对照组(64.29%,P<0.01).2组引产时间、新生儿Apgar评分无显着差异。提示:米索前列醇用于足月妊娠引产可有效地促进宫颈成熟并发动宫缩。

关键词: 米索前列醇, 引产, 子宫收缩

Abstract: To research the efficacy of misoprostol for induced term labor. 91 patients with an indication for induction of labor were assigned to two groups.The induction was carried out either with misoprostol, 50 μg intravaginally every 12 hours until active labor, or with installing valium for 3 days, then augment oxytocin continuously up to labor onset. The mean change in the Bishop score was higher in those receiving misoprostol (2.69 vs 1.80, P<0.05). The rate of efficiency was higher in those receiving misoprostol (93.88% vs 64.29%, P<0.01). No significant differences were noted in the time from induction to vaginal delivery between the two groups. The vaginally administered misoprostol is an effective agent for the cervical ripening and induction of labor.

Key words: misoprostol, induced labor, uterine contraction

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