首都医科大学学报 ›› 2001, Vol. 22 ›› Issue (4): 357-358.

• 论著 • 上一篇    下一篇

咪唑安定镇静在神外术后躁动病人的应用

钱珂, 李淑琴   

  1. 首都医科大学附属北京天坛医院ICU
  • 收稿日期:2000-11-09 修回日期:1900-01-01 出版日期:2001-10-15 发布日期:2001-10-15

The Sedative Action of Midazolam in the Treatment of Neurosurgically Postoperative Restlessness

Qian Ke, Li Shuqin   

  1. Department of Intensive Care Unit, Beijing Tiantan Hospital, Affiliate of Capital University of Medical Sciences
  • Received:2000-11-09 Revised:1900-01-01 Online:2001-10-15 Published:2001-10-15

摘要: 观察咪唑安定对神经外科术后躁动病人的镇静作用.发现给予咪唑安定负荷剂量静注后,躁动病人93%的时间镇静效果满意,平均剂量0.086mg/kg,达到Ramsay 3级镇静水平.持续静脉输注咪唑安定[药量平均0.08mg/(kg·h)],停药后苏醒时间短,长时间应用未见蓄积作用,镇静程度易控制,不良反应少.

关键词: 术后躁动, 静脉镇静, 咪唑安定

Abstract: The purpose of this research is to study the sedative action of midazolam in the treatment of neurosurgically post-operative restlessness. Patients were intravenously given midazolam loading dosage(average 0.086 mg/kg), and during 93% of the whole period patients could reach level 3 of Ramsay sedative condition. The intravenous maintaining midazolam dosage was about 0.08 mg/(kg·h), patients could awake quickly after the drug withdraws and there was no evidence of accumulation after long term midazolam usage. The use of midazolam in neurosurgical post operative restlessness is associated with easily controled sedative level, less side-effect and specific antagonist.

Key words: post-operative restlessness, intravenous sedation, midazolam

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