PC-MRA对Stanford B型主动脉夹层血流动力学与顺应性的研究

doi:10.3969/j.issn.1006-7795.2013.03.002

首都医科大学学报 ›› 2013, Vol. 34 ›› Issue (3): 333-338.doi: 10.3969/j.issn.1006-7795.2013.03.002

PC-MRA对Stanford B型主动脉夹层血流动力学与顺应性的研究

耿冀¹, 范占明², 李宇², 辛海燕², 张楠²

1. 北京大学首钢医院医学影像中心,北京 100144;
2. 首都医科大学附属北京安贞医院放射科,北京 100029

收稿日期:2013-03-05 出版日期:2013-06-21 发布日期:2013-06-17
通讯作者: 范占明 E-mail:fanzm120@tom.com
基金资助:
国家自然科学基金面上项目(30970822)。

Hemodynamics and compliance of Stanford type B aortic dissection: a phase-contrast MR angiography study

GENG Ji¹, FAN Zhanming², LI Yu², XIN Haiyan², ZHANG Nan²

1. Department of Medical Imaging, Peking University Shougang Hospital, Beijing 100144, China;
2. Department of Medical Imaging, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

Received:2013-03-05 Online:2013-06-21 Published:2013-06-17
Supported by:
This study was supported by the National Natural Science Foundation of China(30970822).

摘要/Abstract

摘要：

目的利用相位对比磁共振血管成像对主动脉夹层(Stanford B型)的血流动力学和顺应性进行研究。方法 25例诊断Stanford B型主动脉夹层患者,覆膜支架腔内隔绝术前行相位对比磁共振血管成像。分别采集6个主动脉层面:1升主动脉瓣上肺动脉分叉水平;2主动脉弓水平;3降主动脉破口以远2 cm水平;4膈水平;5平较低支肾动脉下1 cm水平;6腹主动脉近髂分叉水平。对图像数据进行定量分析,测量各层面1个心动周期内真腔与假腔的平均横断面积、血流指标(平均血流速度、平均血流量和净流量),并计算真腔与假腔的顺应性。比较真、假腔平均横断面积、血流指标、顺应性的差异及真、假腔顺应性的相关性。相关性应用Pearson 相关分析,差异比较应用Paired t-test统计学方法。结果在3~6层面水平,所有患者的真腔平均横断面积均小于假腔平均横断面积(P<0.05);真腔内平均血流速度均高于假腔内平均血流速度(P=0.000)。在5、6层面水平,真腔内平均血流量、净流量均高于假腔内平均血流量、净流量(P<0.05)。在3、6层面水平,真腔的顺应性高于假腔的顺应性(P<0.05),并且二者呈明显正相关(r=0.667,P=0.001;r=0.545,P=0.019)。结论相位对比磁共振血管成像能够定量测定主动脉夹层真腔和假腔的血流动力学指标与真假腔顺应性,为临床Stanford B型主动脉夹层患者提供了一种无创的血流动力学监测手段。

关键词: 主动脉夹层, 磁共振血管成像, 相位对比, 血流动力学, 顺应性

Abstract:

Objective To evaluate the characteristics of hemodynamics and compliance using phase-contrast magnetic resonance angiography (PC-MRA) in Stanford type B aortic dissection patients.Methods A total of 25 consecutive patients with Stanford type B aortic dissection identified by computed tomography angiography were recruited in this study. All patients underwent PC-MRA before operation. The cross-sectional images of aorta for PC-MRA were acquired at the following 6 locations: 1pulmonary bifurcation;2aortic arch; 32 cm distal to the entry;4diaphragm;51 cm distal to the lower renal artery;6aorta-iliac bifurcation. Mean area, flow characteristics (including mean velocity, mean flow volume, net volume) of true and false lumens within one cardiac cycle were measured by using PC-MRA. The compliances of true and false lumens were also calculated. Paired t-test and Pearson correlation analysis were involved in statistical analysis Results The mean area of true lumen was significantly smaller than that of false lumen at location 3~6 (P<0.05); the mean velocity in true lumen was significantly higher than that in false lumen at 3~6 levels (P=0.000). At location 5、6, the mean flow volume and net volume in true lumen were significantly higher than that in false lumen (P<0.05). At location 3、6, the compliance of true lumen was significantly higher than that of false lumen (P<0.05), and positive correlation were found between them (r=0.667,P=0.001;r=0.545,P=0.019). Conclusion PC-MRA can quantitatively measure flow characteristics and compliance of true and false lumen in Stanford type B aortic dissection. It is important to provide a noninvasive hemodynamic monitoring tool for Stanford type B aortic dissection.

Key words: aortic dissection, magnetic resonance angiography, phase contrast, hemodynamics, compliance

中图分类号:

R554⁺.1

耿冀, 范占明, 李宇, 辛海燕, 张楠. PC-MRA对Stanford B型主动脉夹层血流动力学与顺应性的研究[J]. 首都医科大学学报, 2013, 34(3): 333-338.

GENG Ji, FAN Zhanming, LI Yu, XIN Haiyan, ZHANG Nan. Hemodynamics and compliance of Stanford type B aortic dissection: a phase-contrast MR angiography study[J]. Journal of Capital Medical University, 2013, 34(3): 333-338.

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PC-MRA对Stanford B型主动脉夹层血流动力学与顺应性的研究

Hemodynamics and compliance of Stanford type B aortic dissection: a phase-contrast MR angiography study

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