心理恐惧对止血带加压性疼痛刺激的预测

doi:10.3969/j.issn.1006-7795.2014.03.014

首都医科大学学报 ›› 2014, Vol. 35 ›› Issue (3): 331-336.doi: 10.3969/j.issn.1006-7795.2014.03.014

心理恐惧对止血带加压性疼痛刺激的预测

许敏, 王坤, 陈昭燃

首都医科大学神经生物学系高级脑功能中心, 北京 100069

收稿日期:2013-10-31 出版日期:2014-06-21 发布日期:2014-06-14
通讯作者: 陈昭燃，E-mail：ac@ccmu.edu.cn E-mail:ac@ccmu.edu.cn
基金资助:
国家自然科学基金（30770691）。

Prediction of the psychological fear on pain sensitivity

Xu Min, Wang Kun, Andrew CN CHEN

Center for Higher Brain Functions, Department of Neurobiology, Capital Medical University, Beijing 100069, China

Received:2013-10-31 Online:2014-06-21 Published:2014-06-14
Supported by:
This study was supported by the National Natural Science Foundation of China(30770691).

摘要/Abstract

摘要：

目的研究止血带加压性疼痛对心率（heart rate，HR）、血压（blood pressure，BP）的影响以及实验前受试者心理状况对疼痛反应的预测性。方法受试者为15名健康年轻成年男性。实验前让受试者填写知情同意书，填写6项心理学量表，以便衡量受试者的心理状况。记录其实验前心率与血压。然后进行3次左上臂（非利手边）止血带加压，连续记录受试者疼痛程度（pain intensity，PI）和不适程度（pain distress，PD），加压速度为10 mmHg/s（1 mmHg=0.133 kPa）。同时记录各次加压前的疼痛阈值（pain threshold，PT）及每次加压刺激后的心率和血压。结果 1）受试者实验前的恐惧量表测量的结果在正常范围内，与其对应的各次加压性疼痛的疼痛阈值变化之间呈负相关（r1=-0.58，P=0.02）。2）疼痛刺激时，心率会随之增加（P<0.03）。3）受试者经每次止血带加压性疼痛刺激，疼痛程度和不适程度都会逐渐升高。结论 1）恐惧评分可以预测止血带加压性的疼痛阈值。2）疼痛刺激能增加心率。

关键词: 止血带加压性疼痛, 恐惧量表, 痛阈, 心率, 疼痛程度, 不适程度

Abstract:

Objective To investigate the prediction of the subject's psychological level on behavioral pain threshold to cuff-pressure tonic pain test and its effect to physical signs of heart rate(HR) and blood pressure(BP). Methods Fifteen healthy young male subjects(age:18-29 years) participated in the study. They were asked to fill in the informed consent and 6 psychological questionnaires, which were used to estimate their psychological level. They all were taken the BP and HR before and after the experiment. Then cuff-pressure pain was induced at their left upper(non-dominated) arms. The pain intensities and the pain distresses were recorded when the stimulus was going at the speed of 10 mmHg/s. Meanwhile, we recorded the pressure-pain thresholds before the stimulus and the HR as well as BP after each cuff-pressure stimulus. Results ① The results of the psychometrics were all in normal limits and the fear level for each subject was negatively correlated with his own values of the 3 cuff pressure pain-thresholds(r=-0.58, P=0.02). ② The HR increased after the pain-test(P<0.03). ③ When teach stimulus was going on, the pain-intensities and the distresses for each subject were increasing gradually. Conclusion ① The result of the fear psychometry can predict the behavioral pain threshold. ② The pain stimulation can increase the HR.

Key words: cuff-pressure pain, fear psychometry, pain threshold, heart rate, pain intensity, pain distress

中图分类号:

R441.1

许敏, 王坤, 陈昭燃. 心理恐惧对止血带加压性疼痛刺激的预测[J]. 首都医科大学学报, 2014, 35(3): 331-336.

Xu Min, Wang Kun, Andrew CN CHEN. Prediction of the psychological fear on pain sensitivity[J]. Journal of Capital Medical University, 2014, 35(3): 331-336.

参考文献

[1] 王海龙, 陈昭燃.止血带加压性疼痛导致交感神经兴奋性的改变[J].中国疼痛医学杂志, 2010, 16(2):76-79.
[2] Polianskis R, Graven-Nielsen T, Arendt-Nielsen L. Computer-controlled pneumatic pressure algometry-a new technique for quantitative sensory testing[J]. Eur J Pain, 2001, 5(3):267-277.
[3] Polianskis R, Graven-Nielsen T, Arendt-Nielsen L. Pressure-pain function in desensitized and hypersensitized muscle and skin assessed by cuff algometry[J]. J Pain, 2002, 3(1):28-37.
[4] Graven-Nielsen T, Segerdahl M, Svensson P, et al. Methods for induction and assessment of pain in human with clinical and pharmacological examples[M]//Kruger L. Methods in pain research.Boca Raton: CRC Press, 2001:264-304.
[5] Curiel García J A, Guerrero-Romero F, Rodríguez-Morán M. Cuff pressure in endotracheal intubation: should it be routinely measured?[J]. Gac Med Mex, 2001, 137(2):179-182.
[6] Lemming D, Graven-Nielsen T, Srensen J, et al. Widespread pain hypersensitivity and facilitated temporal summation of deep tissue pain in whiplash associated disorder: an explorative study of women[J]. J Rehabil Med, 2012, 44(8):648-657.
[7] Chandran A B, Coon C D, Martin S A, et al. Sphygmomanometry-evoked allodynia in chronic pain patients with and without fibromyalgia[J]. Nurs Res, 2012, 61(5):363-368.
[8] Rollnik J D, Kugler J, KrÜskemper G M. Change sensitivity and construct validity of the revised multi-dimensional pain scale[J]. Schmerz, 1998, 12(6):406-410.
[9] Polianskis R, Graven-Nielsen T, Arendt-Nielsen L. Spatial and temporal aspects of deep tissue pain assessed by cuff algometry[J]. Pain, 2002, 100(1-2):19-26.
[10] Bandura A.Self-efficacy scale: toward a unifying theory of behavioral change[J]. Psychol Rev, 1977, 84(2):191-215.
[11] Geer J H. Fear Survey Schedule-Ⅱ. In K. Corcoran and J. Fischer(Eds) Measure for Clinical Practice: A Sourcebook[M]. New York: Free Press, 1987:160.
[12] 解亚宁.简易应对方式问卷[J].中国心理卫生杂志, 1999(增刊):122-124.
[13] Pechlivanova D M, Markova P P, Stoynev A G. Effect of the AT₁receptor antagonist losartan on diurnal variation in pain threshold in spontaneously hypertensive rats[J]. Methods Find Exp Clin Pharmacol, 2010, 32(9): 663-668.
[14] Han J Y, Kim C S, Lim K H, et al. Increases in blood pressure and heart rate induced by caffeine are inhibited by(-)-epigallocatechin-3-O-gallate: involvement of catecholamines[J]. J Cardiovasc Pharmacol, 2011, 58(4):446-449.
[15] Wehlage S J, Smith F G. Nitric oxide and angiotensin Ⅱ regulate cardiovascular homeostasis and the arterial baroreflex control of heart rate in conscious lambs[J]. J Renin Angiotensin Aldosterone Syst, 2012, 13(1):99-106.
[16] Goffredo Filho G S, Faerstein E. Temporary limitations in daily routine activities: association with arterial pressure and antihypertensive therapy[J]. Arq Bras Cardiol, 2010, 94(4):472-476.
[17] 范江宏, 吴承芳, 孟秀华, 等.心理干预对根管治疗畏惧患儿的辅助作用[J].中国煤炭工业医学杂志, 2013, 16(9):1561-1564.
[18] Soyupek S, Bozlu M, Armağan A, et al. Does experimental pain assessment before biopsy predict for pain during transrectal ultrasound-guided prostate biopsy?[J]. Urology, 2007, 70(4):681-684.

心理恐惧对止血带加压性疼痛刺激的预测

Prediction of the psychological fear on pain sensitivity

PDF

可视化

被引次数

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 12

编辑推荐

Metrics

本文评价

[1]	张震, 王冬慧, 孙娜, 王岳青, 韩璐瑶, 谢颖桢, 何玉梅. 失眠伴焦虑患者的脑功能及心率变异性分析[J]. 首都医科大学学报, 2021, 42(3): 464-469.
[2]	曾俊杰, 郭艾. 膝骨关节病股骨后髁偏心距和偏心率特点及其与胫骨平台后倾角相关性分析[J]. 首都医科大学学报, 2019, 40(4): 528-532.
[3]	郑华, 李洁, 王海燕, 李辉, 周辉, 原标, 田宇. 成人体位性心动过速综合征82例临床特征[J]. 首都医科大学学报, 2016, 37(3): 400-404.
[4]	马振山;黄建华;邵军;贾爱华. 晚期癌痛患者在家中镇痛治疗的意义[J]. 首都医科大学学报, 2003, 24(3): 305-306.
[5]	杜凤和;刘金;张彤;李明月;赵继宗;富壮. 急性颅脑损伤患者心率变异性的临床分析[J]. 首都医科大学学报, 2000, 21(3): 204-205.
[6]	杜凤和;徐秀英. 原发性高血压病人血压昼夜节律变化与心率变异的相关分析[J]. 首都医科大学学报, 1999, 20(1): 32-34.
[7]	冯伟捷;张剑峰. 42例急性心肌梗塞患者24h动态血压的变化[J]. 首都医科大学学报, 1998, 19(4): 335-338.
[8]	张化冬;于东明;李继红. 年龄、心率与左室充盈参数的相关性分析[J]. 首都医科大学学报, 1997, 18(4): 333-336.
[9]	华琦. 超声心动图观察年龄、性别及心率等因素对心动周期各时相的影响[J]. 首都医科大学学报, 1994, 15(2): 126-132.
[10]	刘北英;李效义;张淑华;张英才;刘曾复. 兔迷走传入成分对氨刺激鼻粘膜引起的心血管反应的影响[J]. 首都医科大学学报, 1990, 11(2): 79-85.
[11]	孟繁英;孙继文. 急性全心缺氧时心率及冠脉流出量变化的观察及其机制探讨[J]. 首都医科大学学报, 1990, 11(1): 5-9.
[12]	李效义;刘北共;张淑华;张英才;刘曾复. 氨刺激兔鼻粘膜引起心血管反应的神经机制分析[J]. 首都医科大学学报, 1987, 8(3): 163-169.