早期非小细胞肺癌切除范围的临床研究

doi:10.3969/j.issn.1006-7795.2016.06.009

首都医科大学学报 ›› 2016, Vol. 37 ›› Issue (6): 763-766.doi: 10.3969/j.issn.1006-7795.2016.06.009

早期非小细胞肺癌切除范围的临床研究

胡牧, 张毅, 许庆生, 刘宝东, 苏雷, 王若天, 支修益

首都医科大学宣武医院胸外科, 北京 100053

收稿日期:2016-10-03 出版日期:2016-12-21 发布日期:2016-12-16
通讯作者: 支修益 E-mail:xiuyizhi2015@163.com
基金资助:
北京市科委重大项目（D14110700020000）资助

Clinical study for resection range for early stage non-small cell lung cancer patients

Hu Mu, Zhang Yi, Xu Qingsheng, Liu Baodong, Su Lei, Wang Ruotian, Zhi Xiuyi

Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China

Received:2016-10-03 Online:2016-12-21 Published:2016-12-16
Supported by:
This study was supported by Beijing Municipal Science and Technology Commission Major Projects (D14110700020000).

摘要/Abstract

摘要： 目的比较肺叶切除和胸腔镜亚肺叶切除在治疗早期非小细胞肺癌的安全性和近期疗效。方法将直径≤2 cm的早期肺癌回顾性分成胸腔镜下亚肺叶切除组和肺叶切除组，比较两组住院手术期间的各项指标（手术时间、手术出血量、术后住院时间、术后合并症）和术后1年病死率及复发率、术后1年肺功能减少比率。结果 2组手术时间比较，亚肺叶切除组短于肺叶切除组（P=0.000）。2组在手术出血量、术后住院时间和术后合并症方面比较，差异无统计学意义（P>0.05）。术后1年对患者进行随访，两组均未发现死亡病例，未发现肿瘤复发转移情况。亚肺叶切除组在术后1年肺功能减少比例中明显优于肺叶切除组，差异有统计学意义（P=0.000）。结论胸腔镜下亚肺叶切除术对于早期非小细胞肺癌患者安全性和有效性在本研究中得到一定证实。

关键词: 非小细胞肺癌, 亚肺叶切除, 肺叶切除, 早期

Abstract: Objective To compare video assisted thoracic surgery(VATS) lobectomy and sublobectomy in the treatment of early stage non-small cell lung cancer on safety and short term follow up. Methods The early lung cancer patients with lesion 2 cm or less in diameter were divided into lobectomy and sublobectomy resection group. Two groups were compared in the hospitalization after operation, operation time, surgical blood loss, postoperative complications and postoperative recurrence at 1-year, mortality and postoperative lung function reduction rate after 1 year. Results Comparing two groups, sublobecomy group had a shorter operation time than lobectomy group (P=0.000). Surgical blood loss, postoperative hospital stay and postoperative complications had no significant difference (P>0.05) between two groups. After 1 year follow-up, no mortality was found in any group, no tumor recurrence or metastasis was found in any group. In sublobectomy group, reduction of lung function 1 year after surgery was obviously better than the ratio of lobectomy group (P=0.000). Conclusion Safety and effectiveness of VATS sublobectomy for early stage non-small cell lung cancer patients compared with lobectomy have been established in this study.

Key words: non-small cell lung cancer, sublobectomy resection, lobectomy, early stage

中图分类号:

R734.2

胡牧, 张毅, 许庆生, 刘宝东, 苏雷, 王若天, 支修益. 早期非小细胞肺癌切除范围的临床研究[J]. 首都医科大学学报, 2016, 37(6): 763-766.

Hu Mu, Zhang Yi, Xu Qingsheng, Liu Baodong, Su Lei, Wang Ruotian, Zhi Xiuyi. Clinical study for resection range for early stage non-small cell lung cancer patients[J]. Journal of Capital Medical University, 2016, 37(6): 763-766.

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早期非小细胞肺癌切除范围的临床研究

Clinical study for resection range for early stage non-small cell lung cancer patients

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