首都医科大学学报 ›› 2018, Vol. 39 ›› Issue (4): 546-551.doi: 10.3969/j.issn.1006-7795.2018.04.013

• 缺血性脑损伤的基础与临床研究 • 上一篇    下一篇

微创减压治疗恶性大脑中动脉脑梗死的临床回顾研究

侯焕峰, 李如娟, 马晓辉, 杨金波   

  1. 邢台市第九医院神经内科, 河北邢台 055250
  • 收稿日期:2018-05-31 出版日期:2018-07-21 发布日期:2018-07-21
  • 通讯作者: 杨金波 E-mail:yjp196@126.com
  • 基金资助:
    国家自然科学基金(81371287)。

Clinical study of minimally invasive decompression in the treatment of malignant middle cerebral artery infarction

Hou Huanfeng, Li Rujuan, Ma Xiaohui, Yang Jinbo   

  1. Department of Neurology, Xingtai City Ninth Hospital, Xingtai 055250, Hebei Province, China
  • Received:2018-05-31 Online:2018-07-21 Published:2018-07-21
  • Supported by:
    This study was supported by National Natural Science Foundation of China (81371287).

摘要: 目的 探讨微创减压治疗恶性脑梗死的临床治疗效果。方法 选取2012年12月至2016年12月就诊的大面积脑梗死并行微创减压治疗的患者13例,其中男性4例,女性9例,年龄22~85岁,≥ 60岁者6例。在发病后180 d通过电话进行随访,采用改良Rankin量表(modified rankin scale,mRS)评分对患者的预后进行评价(mRS评分≤ 2分为预后良好,mRS评分>2分为预后不良)。结果 13例中4例在3 d内死于脑疝及相关的严重合并症,病死率为30.8%,95% CI:9%~61%。1例在1个月后死于胆结石上消化道大出血。8例存活者中mRS评分≤ 2者5例,mRS评分>2者3例。无微创手术相关的颅内感染、出血及硬膜下血肿等合并症。结论 微创减压治疗恶性大脑中动脉脑梗死可以显著降低病死率。本方法不受年龄局限,方法简单、快捷、安全、有效,无明显手术相关的合并症。

关键词: 恶性大脑中动脉脑梗死, 微创减压术, 脑水肿, 脑肿胀

Abstract: Objective To study the effect of minimally invasive decompression on the treatment of malignant middle cerebral artery infarction. Method There were 13 cases under minimally invasive decompression in the treatment of massive cerebral infarction from December 2012 to December 2016 in our department, 4 male cases, 9 female cases, and aged from 22 to 85 years old, of which 6 cases with patients older than 60 years. The telephone follow-up was conducted at 180th day after the attack, and the modified Rankin cale (mRS) was used to evaluate prognosis. mRS ≤ 2 scored favorable prognosis, mRS>2 scored unfavorable prognosis. Result 4 cases among 13 cases died from cerebral hernia and associated severe complications, and the death rate was 30.8%. 1 case died from massive hemorrhage of upper gastrointestinal tract gallstones. There were 5 cases of mRS ≤ 2, and 3 cases of mRS>2 among 8 survivor cases. There was no complication, such as intracranial infection, hemorrhage or subdural hematoma. Conclusion Minimally invasive decompression in the treatment of malignant middle cerebral artery infarction decreased significantly the death rate. This method was simple, fast, safe, and effective, without age limit and complication.

Key words: malignant middle cerebral artery infarction, minimally invasive decompression, brain edema, cerebral swelling

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