关键词: 脑震荡, 轻型颅脑损伤, 辨证论治, 用药规律

Abstract: Objective To explore the clinical characteristics of concussion patients, traditional Chinese medicine (TCM) syndrome type distribution and prescription regularity. Methods The clinical characteristics and syndrome types of 54 patients with concussion were analyzed with the method of case analysis, and the prescription regularity of TCM for concussion were analyzed based on association rules and complex system entropy clustering algorithm. Results The ratio of male to female in 54 concussion patients was 1.5:1. The average age of the enrolled patients was (39.69±16.34) years old. Young crowd aged between 20-50 years old were in majority. Traffic accident injury was the first cause of mild traumatic brain injury. The main clinical symptoms were dizziness, headache, insomnia, forgetfulness, irritability, depression, poor appetite, nausea, and so on. Phlegm stasis obstruction was the core pathogenesis of concussion. The main TCM syndrome type included qi deficiency and phlegm stasis, heart-kidney imbalance and stasis, liver depression and phlegm stasis, and kidney deficiency and phlegm stasis. Qi deficiency and phlegm stasis was the most important syndrome type. Semen Persicae, Acorus Tatarinowii, Poria Cocos, Ligusticum Chuanxiong, Rhizoma Pinelliae(processed with alum) were the basic herbs for concussion treatment. Conclusion TCM syndrome differentiation was the key point to the concussion treatment. Phlegm stasis obstruction was the core pathogenesis of concussion. Qi deficiency and phlegm stasis was the most important syndrome type. The basic prescription was Semen Persicae, Acorus Tatarinowii, Poria Cocos, Ligusticum Chuanxiong, Rhizoma Pinelliae(processed with alum). The patients with different syndrome type were treated with the corresponding addition and subtraction of Chinese herbs in the formula according to the syndromes differentiation.

Key words: concussion, mild traumatic brain injury, treatment based on syndrome differentiation, prescription regularity