电子计算机断层扫描引导下经皮肺穿刺活检磨玻璃结节的诊断价值

doi:10.3969/j.issn.1006-7795.2022.04.008

首都医科大学学报 ›› 2022, Vol. 43 ›› Issue (4): 558-563.doi: 10.3969/j.issn.1006-7795.2022.04.008

• 肺癌一体化诊断和治疗 • 上一篇下一篇

电子计算机断层扫描引导下经皮肺穿刺活检磨玻璃结节的诊断价值

钱坤, 赵昕, 谭晓刚, 田笑如, 刘幸生, 张毅^*

首都医科大学宣武医院胸外科,北京 100053

收稿日期:2022-04-13 出版日期:2022-08-21 发布日期:2022-10-28
基金资助:
首都医学发展科研基金(2022-2-2013)。

Diagnostic value of computed tomography guided percutaneous transthoracic needle biopsy (PTNB) for ground-glass nodule

Qian Kun, Zhao Xin, Tan Xiaogang, Tian Xiaoru, Liu Xingsheng, Zhang Yi^*

Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China

Received:2022-04-13 Online:2022-08-21 Published:2022-10-28
Contact: *E-mail:steven9130@sina.com
Supported by:
This study was supported by Capital Medical Development Research Fund (2022-2-2013).

摘要/Abstract

摘要： 目的探讨电子计算机断层扫描(computed tomography,CT)引导下经皮肺穿刺活检磨玻璃结节(ground-glass nodule, GGN)的诊断价值。方法回顾性分析 2014年1月至2019年1月期间 217例接受 CT 引导下经皮肺穿刺活检的 GGN 患者的临床病理资料,对穿刺为恶性的病例判断为阳性,对于穿刺为良性的患者结合随访结果做出临床诊断,将穿刺病理与临床最终诊断作对比。根据临床特点进行分组,统计分析每组穿刺活检的准确率、灵敏度、阴性预测值及并发症发生率。结果 217例患者总体准确率93.5%(203/217),灵敏度92.2%(165/179),阴性预测值为73.1%(38/52)。并发症总体发生率35.5%,以咯血和气胸为主。结论 CT引导下对GGN穿刺活检具有较高的准确性和灵敏度,但需要警惕假阴性的结果,妥善处理并发症。

关键词: 磨玻璃结节, 活检, 诊断价值

Abstract: Objective To investigate the diagnostic value of computed tomography(CT) guided percutaneous transthoracic needle biopsy (PTNB) for ground-glass nodule (GGN). Methods The clinicopathological data of 217 patients with GGN who underwent CT guided PTNB from January 2014 to January 2019 were retrospectively analyzed. The cases with malignant puncture were judged to be positive. The patients with benign puncture were clinically diagnosed in combination with the follow-up results, and the puncture pathology was compared with the final clinical diagnosis. The accuracy, sensitivity, negative predictive value, and complication rate of puncture biopsy in each group were statistically analyzed. Results The overall accuracy of 217 patients was 93.5% (203/217), the sensitivity was 92.2% (165/179), and the negative predictive value was 73.1% (38/52). The overall incidence of complications was 35.5%, mainly hemoptysis and pneumothorax. Conclusion CT guided PTNB GGN had high accuracy and sensitivity. It is necessary to be vigilant against false negative results and properly deal with complications.

Key words: ground-glass nodule, biopsy, diagnostic value

中图分类号:

R655.3

钱坤, 赵昕, 谭晓刚, 田笑如, 刘幸生, 张毅. 电子计算机断层扫描引导下经皮肺穿刺活检磨玻璃结节的诊断价值[J]. 首都医科大学学报, 2022, 43(4): 558-563.

Qian Kun, Zhao Xin, Tan Xiaogang, Tian Xiaoru, Liu Xingsheng, Zhang Yi. Diagnostic value of computed tomography guided percutaneous transthoracic needle biopsy (PTNB) for ground-glass nodule[J]. Journal of Capital Medical University, 2022, 43(4): 558-563.

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电子计算机断层扫描引导下经皮肺穿刺活检磨玻璃结节的诊断价值

Diagnostic value of computed tomography guided percutaneous transthoracic needle biopsy (PTNB) for ground-glass nodule

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