双相情感障碍复发相关的社会心理特征因素研究

doi:10.3969/j.issn.1006-7795.2023.04.016

摘要/Abstract

摘要： 目的探索影响双相情感障碍（ bipolar disorder，BD）复发的社会心理特征。方法选取2020年8月至2022年1月间于首都医科大学附属北京安定医院门诊就诊的BD患者共计269例，根据BD是否发作分为发作组（194例）和稳定组（75例），统计两组患者的基本信息、临床特征、药物依从性、情感气质、社会支持、儿童期创伤和五态人格之间的差异，再以逻辑回归和中介效应确定BD复发相关的危险因素及其之间的中介关系。结果循环气质、激惹气质、太阴人格与BD复发成正相关，而客观社会支持与BD复发成负相关；客观社会支持与抑郁情绪之间存在直接效应，效应值为-0.08；循环气质和太阴人格皆在客观社会支持与抑郁情绪之间有中介作用，中介值分别为-0.018和-0.028，总的间接效应为-0.046，客观社会支持与抑郁情绪之间的总效应值为-0.127，中介作用占总效应的36.2%。结论 BD患者接受到的客观社会支持越多，抑郁情绪的水平越低，基于人格和气质的社会心理干预可能有助于改善社会支持不佳引起的BD复发。

关键词: 双相情感障碍, 社会心理特征, 循环气质, 五态人格, 复发

Abstract: Objective To explore the psychosocial characteristics affecting relapse of bipolar disorder (BD). Methods A total of 269 BD patients from the outpatient department of Beijing Anding Hospital Affiliated to Capital Medical University from August 2020 to January 2022 were selected and divided into group of mood episode and group of non-mood episode. The differences of basic information, clinical characteristics, medication compliance, affective temperament, social support, childhood trauma and five-pattern personality of the two groups were analyzed. Then logical regression and mediating effect were used to determine the risk factors related to BD recurrence and the mediating relationship of these factors. Results Cyclothymic temperament, irritable temperament and Taiyin personality were positively correlated with BD relapse, while objective social support was negatively correlated with BD relapse. There was a direct effect between objective social support and depression, with an effect value -0.08. Both Cyclothymic temperament and Taiyin personality had mediating effects between objective social support and depressive mood, with the mediating values -0.018 and -0.028, respectively, and the total indirect effect was -0.046. The total effect value between objective social support and depressive mood was -0.127, and the mediating effect accounted for 36.2% of the total effect. ConclusionsThe more objective social support BD patients received, the lower the level of depressive mood. Social psychological intervention based on personality and temperament may help to suppress the recurrence of BD caused by poor social support.

Key words: bipolar disorder, psychosocial characteristics, cyclic temperament, five-state personality, relapse

中图分类号:

R749.4

闫爱国, 刘鑫子, 尹冬青, 朱虹, 贾竑晓, 李自艳. 双相情感障碍复发相关的社会心理特征因素研究[J]. 首都医科大学学报, 2023, 44(4): 602-608.

Yan Aiguo, Liu Xinzi, Yin Dongqing, Zhu Hong , Jia Hongxiao , Li Ziyan. Psychosocial characteristics associated with relapse of bipolar disorder[J]. Journal of Capital Medical University, 2023, 44(4): 602-608.

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