首都医科大学学报 ›› 2026, Vol. 47 ›› Issue (1): 135-142.doi: 10.3969/j.issn.1006-7795.2026.01.017

• 基础研究 • 上一篇    下一篇

喷砂参数对含氯生物活性玻璃喷料清除牙面色素效能的影响

李飘#,屈英杰#,欧阳泽驰,刘欧胜,陈晓婧*   

  1. 中南大学湘雅口腔医学院材料学教研室;口腔健康研究湖南省重点实验室;口腔颌面再生王松灵院士专家工作站,长沙 410008
  • 收稿日期:2025-10-13 修回日期:2025-11-04 出版日期:2026-02-21 发布日期:2026-02-02
  • 通讯作者: 陈晓婧 E-mail:xiaojing.chen@csu.edu.cn
  • 基金资助:
    湖南省自然科学基金重点项目(2025JJ30045),湖南省青年托举工程(2023TJ-N18),长沙市杰出创新青年培养计划(kq2305026)。

Effect of air-abrasion parameters on the efficacy of chloride-containing bioactive glass abrasives in removing dental extrinsic stains

Li Piao#, Qu Yingjie#, Ouyang Zechi, Liu Ousheng, Chen Xiaojing*   

  1. Department of Dental Materials, Xiangya School of Stomatology, Xiangya Stomatological Hospital  Central South University;Hunan Key Laboratory of Oral Health Research;Academician Workstation for Oral-maxilofacial and Regenerative Medicine, Changsha 410008, China
  • Received:2025-10-13 Revised:2025-11-04 Online:2026-02-21 Published:2026-02-02
  • Supported by:
    This study was supported by Key Project of Hunan Provincial Natural Science Foundation (2025JJ30045), Technology Talent Lifting Project of Hunan Province (2023TJ-N18), Changsha Prominent Young Innovators Program (kq2305026).

摘要: 目的  探究喷砂压力、距离和角度对含氯化物生物活性玻璃(chlorine-containing bioactive glass,Cl-BG)喷砂效能(以釉质去除量表征)及牙面色素清除效果的影响,并与临床常用喷料碳酸氢钠(sodium bicarbonate, NaHCO3)进行比较。方法  采用激光粒度仪和扫描电镜表征Cl-BG和NaHCO3的粒度与形貌;CCK-8法评估细胞毒性。使用牛牙釉质通过白光干涉仪定量分析不同喷砂参数(压力:20、40、60 psi;距离:2、5 mm;角度:45°、90°)下Cl-BG的釉质去除量。构建人离体牙色素模型,通过体视显微镜和扫描电镜可视化观测两种喷料在设定参数下的牙面色素去除效果。结果  Cl-BG与NaHCO3粒径相近,均无细胞毒性。Cl-BG的釉质去除量随喷砂压力增加而增大,改变压力时体积的变化幅度,比改变距离时的变化更明显。在相同的参数下,Cl-BG喷料的色素清除效果优于NaHCO3组。在Cl-BG组中, 90°角度的去除效率高于45°,距离的变化对去除效果的影响较小。扫描电镜显示Cl-BG处理后釉质表面有颗粒残留,提示其再矿化潜力。结论  喷砂效能主要受压力调控。Cl-BG喷料在高效清除牙面色素的同时,兼具生物安全性及促进再矿化的潜能,是一种极具应用前景的新型微创牙科喷料。

关键词: 含氯生物活性玻璃, 空气喷砂, 牙面色素, 釉质磨损, 喷砂参数, 碳酸氢钠

Abstract: Objective  To investigate the effects of air-abrasion parameters, including pressure, distance, and angle on the abrasive efficacy and extrinsic stain removal effect of chloride-containing bioactive glass abrasives (Cl-BG). Methods  With commonly used abrasive sodium bicarbonate (NaHCO3) as the control, the particle size and morphology of Cl-BG were characterized using a laser particle size analyzer and scanning electron microscope (SEM), and their cytotoxicity was evaluated with a CCK-8 assay. The enamel removal volume on bovine enamel by Cl-BG under different air-abrasion parameters (pressure: 20, 40, 60 psi; distance: 2, 5 mm; angle: 45°, 90°) was quantitatively analyzed using a white light interferometry. An extrinsic stain model on extracted human teeth was established, and the stain removal effects of the two abrasives under set parameters were visually observed using stereomicroscopy and SEM. Results  Cl-BG and NaHCO3 had similar particle sizes and both showed no cytotoxicity. The enamel removal volume by Cl-BG increased with increasing air-abrasion pressure, while the influences of the angle and distance were less significant. Under identical parameters, the stain removal effect of Cl-BG was superior to that of the NaHCO3. Within the Cl-BG group, the removal efficiency at a 90° angle was  found to be superior to than at 45°. SEM observations revealed the presence of residual glass particles on the enamel surface after treatment, providing a potential remineralization ability. Conclusion  Air-abrasion efficacy is primarily regulated by pressure. It demonstrated that Cl-BG was an effective agent for the removal of  dental extrinsic stains. The good biocompatibility and the potential to promote remineralization made it a highly promising novel abrasive for minimally invasive dentistry.

Key words: chlorine-containing bioactive glass, air abrasion, extrinsic dental stains, enamel abrasion, air-abrasion parameter, sodium bicarbonate

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